Catalog No.
VVV25501
Species reactivity
Junin mammarenavirus (JUNV) (Junn mammarenavirus)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC
Concentration
7.76 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
C1K9J9
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
100 mM Pro-Ac, 20 mM Arg, pH 5.0.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
JUN1#
A hTfR1 Receptor-Specific VHH Antibody Neutralizes Pseudoviruses Expressing Glycoproteins from Junín and Machupo Viruses., PMID:39772257
Glycoprotein-Specific Polyclonal Antibodies Targeting Machupo Virus Protect Guinea Pigs against Lethal Infection., PMID:38932403
Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies., PMID:35315691
Immunization with GP1 but Not Core-like Particles Displaying Isolated Receptor-Binding Epitopes Elicits Virus-Neutralizing Antibodies against Junín Virus., PMID:35214632
Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain., PMID:34132574
Bivalent Junin & Machupo experimental vaccine based on alphavirus RNA replicon vector., PMID:32111526
Development of horse neutralizing immunoglobulin and immunoglobulin fragments against Junín virus., PMID:31760108
Neutralization of Junín virus by single domain antibodies targeted against the nucleoprotein., PMID:30061671
Novel neutralizing monoclonal antibodies against Junin virus., PMID:29870772
Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses., PMID:29760382
Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization., PMID:28630325
Differences in Glycoprotein Complex Receptor Binding Site Accessibility Prompt Poor Cross-Reactivity of Neutralizing Antibodies between Closely Related Arenaviruses., PMID:28100617
Molecular Basis for Antibody-Mediated Neutralization of New World Hemorrhagic Fever Mammarenaviruses., PMID:26651946
For research use only. Not for human or drug use.
