Catalog No.
YMK81401
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Glu67-Glu311
Predicted molecular weight
29.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8VE43
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Meteorin-like protein, Subfatin, Metrnl
METRNL represses beta-to-alpha cell trans-differentiation to maintain beta cell function under diabetic metabolic stress in mice., PMID:40495021
The Effects of Meteorin-Like Protein on Diabetic Neuropathy: In Vivo and In Vitro Model Studies., PMID:40444602
Cellular crosstalk mediated by Meteorin-like regulating hepatic stellate cell activation during hepatic fibrosis., PMID:40393967
The correlation between serum asprosin and type 2 diabetic patients with obesity in the community., PMID:40391011
TNFRSF11B-modified umbilical cord mesenchymal stem cells as a novel strategy for bone-related diseases by suppressing osteoclast activity., PMID:40380204
Dual role of Metrnl: exercise-induced benefits and potential cancer implications., PMID:40341022
Meteorin-like protein (Metrnl): a key exerkine in exercise-mediated cardiovascular health., PMID:40289582
Exercise-induced meteorin-like protein protects human pancreatic beta cells from cytokine-induced apoptosis., PMID:40220193
Exploring METRNL as a novel biomarker in sepsis: diagnostic potential and secretion mechanism., PMID:40205457
Metrnl protects intestinal barrier function by regulating tight junctions via the IKKβ/IκBα/NFκB/MLCK/MLC signaling pathway., PMID:40199887
Myokines as potential mediators of changes in glucose homeostasis and muscle mass after bariatric surgery., PMID:40171198
The diagnostic potential of Asprosin and Meteorin-like proteins in basal and squamous cell carcinomas., PMID:40095046
Metrnl ameliorates myocardial ischemia-reperfusion injury by activating AMPK-mediated M2 macrophage polarization., PMID:40082768
Metrnl Ameliorates Ferroptosis in Model of Diabetic Foot Ulcer Through the Inhibition of Mitochondrial Damage via LKB1/AMPK Signaling., PMID:40073879
Metrnl/C-KIT Axis Attenuates Early Brain Injury Following Subarachnoid Hemorrhage by Inhibiting Neuronal Ferroptosis., PMID:39981761
Downregulation of miR-410-3p via the METRNL-mediated AMPK/SIRT1/NF-κB signaling axis inhibits oxidative stress and inflammation in idiopathic pulmonary fibrosis., PMID:39971221
Meteorin-like levels of oral fluids in periodontal health and diseases: a comparative cross-sectional study., PMID:39964474
Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study., PMID:39922928
Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation., PMID:39918960
Myokines: metabolic regulation in obesity and type 2 diabetes., PMID:39872377
Association between Metrnl and carotid atherosclerosis in patients with type 2 diabetes mellitus., PMID:39845885
Higher serum Metrnl levels are associated with increased vascular calcification in hemodialysis patients., PMID:39842817
Meteorin-like protein plasma levels are associated with worse outcomes in de novo heart failure., PMID:39834188
Investigation into the molecular mechanisms of biomarkers in psoriasis vulgaris with reduced high-density lipoprotein levels based on bulk transcriptome sequencing data., PMID:39732346
Housing temperature influences exercise-induced glucose regulation and expression of exerkines in mice., PMID:39721028
Meteorin-like protein alleviates intervertebral disc degeneration by suppressing lipid accumulation in nucleus pulposus cells via PPARα-CPT1A activation., PMID:39706351
IL-41: A novel serum marker correlates with disease activity in patients with ankylosing spondylitis., PMID:39614798
METRNL exerts cytoprotective effects on EPCs via regulation of the E2F1-TXNIP axis in obese limb ischemia., PMID:39603439
Metrnl/IL-41 Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Inflammatory Responses through the AMPK/SIRT1 Signaling Pathway., PMID:39581185
Adipokines and their potential impacts on susceptibility to myocardial ischemia/reperfusion injury in diabetes., PMID:39538244
Association of serum Metrnl levels and high-density lipoprotein cholesterol in patients with type 2 diabetes mellitus: a cross-sectional study., PMID:39421410
Metrnl as a secreted protein: Discovery and cardiovascular research., PMID:39401532
Investigation of serum Metrnl levels in pregnant women with gestational diabetes mellitus: a prospective non-interventional cohort study., PMID:39383393
Low serum Metrnl levels are associated with increased risk of sarcopenia in the older adults., PMID:39361190
Elevated meteorin-like protein from high-intensity interval training improves heart function via AMPK/HDAC4 pathway., PMID:39281832
Unveiling the Effects of Interval Resistance Training and Chlorella Vulgaris Supplementation on Meteorin-like Protein and Oxidative Stress in Obese Men., PMID:39279784
Single-cell RNA sequencing identifies inherent abnormalities of adipose-derived stem cells from nonlesional sites of patients with localized scleroderma., PMID:39215271
Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target., PMID:39190657
The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function., PMID:39111315
Metrnl: a promising biomarker and therapeutic target for cardiovascular and metabolic diseases., PMID:39103830
The Plasma Levels of Protein Adiponectin (AdipoQ) and Meteorin-Like (Metrnl) in Newly Diagnosed Type 2 Diabetes Mellitus., PMID:39100966
The Novel Cytokine Interleukin-41/Meteorin-like Is Reduced in Diffuse Systemic Sclerosis., PMID:39056787
Olink Profiling of Aqueous Humor Identifies Novel Biomarkers for Wet Age-Related Macular Degeneration., PMID:38902972
Correlation of serum Meteorin-like (Metrnl) level with type 2 diabetic peripheral neuropathy., PMID:38849768
Organokines and liver enzymes in adolescent girls with polycystic ovary syndrome during randomized treatments., PMID:38818508
Metrnl inhibits choroidal neovascularization by attenuating the choroidal inflammation via inactivating the UCHL-1/NF-κB signaling pathway., PMID:38745648
Meteorin-like protein/METRNL/Interleukin-41 ameliorates atopic dermatitis-like inflammation., PMID:38727640
Impact of 8-week cold-and warm water swimming training combined with cinnamon consumption on serum METRNL, HDAC5, and insulin resistance levels in diabetic male rats., PMID:38681576
Circulating levels of irisin and Meteorin-like protein in PCOS and its correlation with metabolic parameters., PMID:38646985
Homotherapy for heteropathy: Interleukin-41 and its biological functions., PMID:38594835
For research use only. Not for human or drug use.
