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Recombinant Human CYP2E1 Protein, N-His

Catalog #:   YHC15201 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P05181
Protein length: Leu32-Ser493
Overview

Catalog No.

YHC15201

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Leu32-Ser493

Predicted molecular weight

55.67 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P05181

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

CYP2E, 4-nitrophenol 2-hydroxylase, CYP2E1, Cytochrome P450 2E1, CYPIIE1, Cytochrome P450-J

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human CYP2E1 protein
References

L-Theanine Mitigates Chronic Alcoholic Intestinal Injury by Regulating Intestinal Alcohol and Linoleic-Arachidonic Acid Metabolism in Rats., PMID:40507212

2'-Fucosyllactose Modulates the Intestinal Immune Response to Gut Microbiota and Buffers Experimental Colitis in Mice: An Integrating Investigation of Colonic Proteomics and Gut Microbiota Analysis., PMID:40501496

Shenzhuo formulation ameliorates diabetic nephropathy by regulating cytochrome P450-mediated arachidonic acid metabolism., PMID:40487618

Development of a TK6-derived cell line expressing four human cytochrome P450s for genotoxicity testing., PMID:40436327

The DNA Repair Protein MGMT Protects against the Genotoxicity of N-Nitrosodimethylamine, but Not N-Nitrosodiethanolamine and N-Nitrosomethylaniline, in Human HepG2 Liver Cells with CYP2E1 Expression., PMID:40390554

A narrative review on alcohol and alimentary tract cancer with special emphasis on acetaldehyde and oxidative stress., PMID:40378880

Optimization of Hesperidin Nanoparticles as a Promising CYP2E1 and CYP3A11 Regulator in Paracetamol-Intoxicated Mice., PMID:40370238

Sugarcane Molasses Polyphenol Extract Attenuates Alcohol-Induced Chronic Liver Damage via Antioxidant, Anti-Inflammatory, and CYP2E1/Keap1/NF-κB Pathway Modulation., PMID:40362898

Gardenin A alleviates alcohol-induced oxidative stress and inflammation in HepG2 and Caco2 cells via AMPK/Nrf2 pathway., PMID:40318507

Discovery of a CYP2E1 inhibitor and its therapeutic potential in severe acute pancreatitis., PMID:40318482

Cytochrome P450 2E1 aggravates DXR-induced myocardial injury through imbalanced mitochondrial OPA1., PMID:40307912

Uncovering the Efficacy of Cinnamomum tamala Leaf Extract Against Paracetamol-Induced Hepatotoxicity in Swiss Albino Mice., PMID:40300760

Sargassum horneri extract attenuates high-dose acetaminophen-induced hepatotoxicity by enhancing the antioxidant activity and inhibiting acetaminophen activation in the mouse liver., PMID:40291109

Acetaldehyde-driven mRNA methylation and expression changes in ethanol-metabolizing enzyme genes., PMID:40252050

In vivo inhibition of CYP2E1 fails to reduce pulegone-induced liver injury in mice., PMID:40249652

The Functional Components and Hepatic Protective Mechanism of Wolfberry Vinegar by Mixed-Culture Fermentation., PMID:40238496

Roles of Oxidative Stress and Autophagy in Alcohol-Mediated Brain Damage., PMID:40227291

Human prostacyclin and thromboxane synthases: Molecular interactions, regulation, and pharmacology., PMID:40222477

The role of cytochrome P4502E1 in ethanol mediated diseases: a narrative update., PMID:40192654

Characterization of hepatic pathology during azoxymethane-induced acute liver failure., PMID:40182596

High dose acetaminophen re-polarizes CD11b+ cells in the tumor microenvironment towards an activated macrophage phenotype., PMID:40158231

Alcohol-Metabolizing Enzymes, Liver Diseases and Cancer., PMID:40157374

Magnesium isoglycyrrhizinate prevented the liver injury of acetaminophen by promoting mitochondrial biogenesis., PMID:40151340

Maternal MitoQ Treatment Is Protective Against Programmed Alterations in CYP Activity Due to Antenatal Dexamethasone., PMID:40142951

Chitosan Oligosaccharides Prevent Alcohol-Induced Liver Disease by Attenuating Inflammation and Oxidative Stress., PMID:40137320

Effects of magnolol on the liver antioxidant status in rats with diabetes., PMID:40126860

Identification of cytochrome P450 2E1 as a novel target in neuroinflammation and development of its inhibitor Q11 as a treatment strategy., PMID:40122152

Liver microsomal protein content and activity in patients with hepatocellular carcinoma and cirrhosis: implications for the in vivo prediction of individual hepatic clearance., PMID:40115928

Cytochrome P450 Enzyme-Mediated Enantioselective Biotransformation of Chiral Fungicide Tebuconazole in Earthworm., PMID:40098277

CYP2A6 suppresses hepatocellular carcinoma via inhibiting SRC/Wnt/β-Catenin pathway., PMID:40069491

Huangqi and Danshen improve the chronic nephrotoxicity of cyclosporin A by regulating lipid metabolism., PMID:40056636

Insights into CdTe quantum dots induced hepatotoxicity: Regulation of cytochromes P450 isoenzymes function in liver microsomes from in vivo and in vitro studies., PMID:40044020

Pharmacogenomics-Based Detection of Variants Involved in Pain, Anti-inflammatory and Immunomodulating Agents Pathways by Whole Exome Sequencing and Deep in Silico Investigations Revealed Novel Chemical Carcinogenesis and Cancer Risks., PMID:40026294

[Application of Human Liver Organoids for Pharmaceutical Research]., PMID:40024731

Acute Acetaminophen Hepatotoxicity And Platelet Dysfunction., PMID:40014260

Comparative study of cytochrome P450 expression in the kidneys of Lepus yarkandensis and Oryctolagus cuniculus., PMID:40011673

Repression of the ERRγ-CYP2E1 pathway by FGF4 mitigates alcohol-associated liver injury., PMID:40009617

Effects of Chronic Alcohol Intake on the Composition of the Ensemble of Drug-Metabolizing Enzymes and Transporters in the Human Liver., PMID:39997363

Protective effects of oral pharmaceutical solution of fucoxanthin against paracetamol-induced liver injury: modulation of drug-metabolizing enzymes, oxidative stress, and apoptotic pathways in rats., PMID:39992072

Quinic acid alleviates liver toxicity induced by acetaminophen in mice via anti-oxidative and anti-inflammatory effects., PMID:39985580

Role of Cytochromes P450 in Intestinal Barrier Function: Possible Involvement in the Pathogenesis of Leaky Gut Syndrome., PMID:39971825

Kehuang capsule inhibits MAPK and AKT signaling pathways to mitigate CCl4-induced acute liver injury., PMID:39958915

Genetic polymorphisms and anti-tuberculosis drug-induced liver injury: an umbrella review of the evidence., PMID:39954223

Mechanism of Regio- and Enantioselective Hydroxylation of Arachidonic Acid Catalyzed by Human CYP2E1: A Combined Molecular Dynamics and Quantum Mechanics/Molecular Mechanics Study., PMID:39932478

Effects of periconceptional ethanol on mitochondrial content and oxidative stress in maternal liver and placentas from male and female fetuses in rats., PMID:39924874

Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice., PMID:39919552

Environmentally persistent free radicals stimulate CYP2E1-mediated generation of reactive oxygen species at the expense of substrate metabolism., PMID:39884817

Effects of acteoside from Cistanche tubulosa on the plasma metabolome of cancer-related fatigue mice inoculated with colon cancer cells., PMID:39872045

Scopoletin alleviates acetaminophen-induced hepatotoxicity through modulation of NLRP3 inflammasome activation and Nrf2/HMGB1/TLR4/NF-κB signaling pathway., PMID:39870009

Lactobacillus extracellular vesicles alleviate alcohol-induced liver injury in mice by regulating gut microbiota and activating the Nrf-2 signaling pathway., PMID:39865864

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human CYP2E1 Protein, N-His [YHC15201]
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