Catalog No.
RHG67402
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Target
Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1, Voltage-dependent L-type calcium channel subunit alpha-1C, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Rat brain class C, RBC, Voltage-gated calcium channel subunit alpha Cav1.2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13936
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
L57/46R
Altered Protein Kinase A-Dependent Phosphorylation of Cav1.2 in Left Ventricular Myocardium from Cacna1c Haploinsufficient Rat Hearts., PMID:39769475
Early transverse tubule involvement in cardiomyocytes in hereditary transthyretin amyloidosis: a possible cause of cardiac events., PMID:35872346
Abnormal levels of mitochondrial Ca2+ channel proteins in plasma neuron-derived extracellular vesicles of early schizophrenia., PMID:35867070
[Rituximab in the treatment of diffuse large B-cell lymphoma: The CACNA1C subunit of channel Cav1.2 expression linked to certain forms of resistance]., PMID:33908862
Exposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice., PMID:31773193
CaV1.2 and CaV1.3 voltage-gated L-type Ca2+ channels in rat white fat adipocytes., PMID:31770099
A bivalent antihypertensive vaccine targeting L-type calcium channels and angiotensin AT1 receptors., PMID:31625597
L-Type Cav 1.2 Calcium Channel-α-1C Regulates Response to Rituximab in Diffuse Large B-Cell Lymphoma., PMID:30824586
Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women., PMID:28807015
L-type calcium channel modulates cystic kidney phenotype., PMID:24925129
Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node., PMID:23045342
The "invulnerability" of the adult conduction system to anti-Ro/SSA antibodies? A matter of calcium channel expression on the cardiomyocyte., PMID:21692891
Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice., PMID:21352396
Exposure to extremely low-frequency (50 Hz) electromagnetic fields enhances adult hippocampal neurogenesis in C57BL/6 mice., PMID:20816824
L-type calcium channel CaV 1.2 in transgenic mice overexpressing human AbetaPP751 with the London (V717I) and Swedish (K670M/N671L) mutations., PMID:20413896
Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension., PMID:19011682
Ryanodine receptor activation by Ca v 1.2 is involved in dendritic cell major histocompatibility complex class II surface expression., PMID:18927079
Chronic morphine treatment decreases the Cav1.3 subunit of the L-type calcium channel., PMID:18048029
Protein kinase G phosphorylates Cav1.2 alpha1c and beta2 subunits., PMID:17626895
Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory., PMID:16251435
Antibodies against the calcium channel beta-subunit in Lambert-Eaton myasthenic syndrome., PMID:9484375
[Molecular immunology of voltage-gated calcium channel and Lambert-Eaton myasthenic syndrome]., PMID:9436458
For research use only. Not for human or drug use.
