Catalog No.
YXX11001
Expression system
E. coli
Species
Escherichia coli
Protein length
Tyr179-Arg541
Predicted molecular weight
41.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A0A0R6L508
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Probable phosphatidylethanolamine transferase Mcr-1, Polymyxin resistance protein MCR-1, mcr1, mcr-1
Persistence of mcr-1-carrying E. coli in rabbit meat production: Challenges beyond long-term colistin withdrawal., PMID:40381227
Integrated Genomic and Phenotypic Characterization of an Mcr-10.1-Harboring Multidrug Resistant Escherichia coli Strain From Migratory Birds in China., PMID:40343190
Shelter dogs as reservoirs of international clones of Escherichia coli carrying mcr-1.1 and blaCTX-M resistance genes in Lima, Peru., PMID:40339258
Plasmid mediated colistin resistance in ESBL producing Enterobacterales based on both phenotypic and molecular analysis in companion and farm animals from Algeria., PMID:40305984
Plasmid-Mediated Co-Occurrence of mcr-1.1 in Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli Isolated From the Indigenous Seminomadic Community in Malaysia., PMID:40303148
Detection and genetic characterisation of ESBL, carbapenemase, and mcr-1 genes in Gram-negative bacterial isolates from companion animals in Batna, Algeria., PMID:40253565
Genome-based assessment of antimicrobial resistance of Escherichia coli recovered from diseased swine in eastern China for a 12-year period., PMID:40243369
Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer., PMID:40234663
Genomic characterization of plasmids of mcr-1-positive Escherichia coli isolated from cohabiting rats, dairy cattle and pigs., PMID:40229806
Genomic insights and epidemiology of mcr-1-Carrying Escherichia albertii isolated from agricultural soil in China., PMID:40188040
OBOC screening of high activity and low-toxic polymyxin analogs against MCR-1 resistant strains., PMID:40178230
Emergence of a clinical carbapenem-resistant Escherichia coli co-harboring blandm-5 and mcr-1.1 on the same plasmid., PMID:40139446
Characterization of antibiotic determinants and heavy metal resistance genes in Escherichia coli from pigs in Catalonia., PMID:40131333
Tenfold multiplex PCR method for simultaneous detection of mcr-1 to mcr-10 genes and application for retrospective investigations of Salmonella and Escherichia coli isolates in China., PMID:40086740
Emergence of plasmid-mediated fosfomycin resistance among Escherichia coli harboring fosA4, tet(X4), and mcr-1 genes in wild birds., PMID:40079598
Repurposing fenticonazole nitrate to restore colistin susceptibility in multidrug-resistant bacteria., PMID:40037503
Colistin and β-lactam resistance in Escherichia coli isolates from bovines, swine, and humans., PMID:39977467
High frequency of chromosomal polymyxin resistance in Escherichia coli isolated from dairy farm animals and genomic analysis of mcr-1-positive strain., PMID:39964669
Complete genome characterization of mcr-1-mediated colistin-resistant Escherichia coli from outpatients in Bulgaria., PMID:39914942
DNA Polymerase IV dinB Favors the Adaptive Fitness of mcr-carrying Bacteria Through a Negative Feedback Regulatory Mechanism., PMID:39887566
Epidemiology of colistin resistance mediated by mcr-1 in carbapenemase-producing Enterobacterales in Ecuador in three periods from 2016 to 2022., PMID:39875307
Glabridin restore the sensitivity of colistin against mcr-1-positive Escherichia coli by polypharmacology mechanism., PMID:39842376
Quaternary Ammonium Compounds: A New Driver and Hidden Threat for mcr-1 Prevalence in Hospital Wastewater and Human Feces., PMID:39818750
Resistome and plasmidome genomic features of mcr-1.1-harboring Escherichia coli: a One Health approach., PMID:39809568
Clinical and molecular analysis of ESBL, carbapenemase, and colistin-resistant bacteria in UTI patients., PMID:39799481
No genetic link between E. coli isolates carrying mcr-1 in bovines and humans in France., PMID:39756652
CTX-M, SHV, TEM and VEB β-lactamases, and MCR-1 among multidrug-resistant Escherichia coli and Klebsiella isolates from environment near animal farms in Thailand., PMID:39740339
Epidemiological and genetic characteristics of clinical carbapenemase-producing Enterobacterales isolates from Batna hospitals in Algeria., PMID:39695434
Investigation of colistin heteroresistance and the colistin resistance genes mcr-1 to mcr-5 in Escherichia coli and Klebsiella pneumoniae isolates in a tertiary hospital in Turkey., PMID:39693153
Environmental mediation of colistin resistance in the African context. A systematic scoping review., PMID:39681218
Investigation on the reversal effect of closantel on colistin resistance in MCR-1 positive Escherichia coli based on dose-response relationship., PMID:39658100
Draft genome sequence of a co-harbouring blaNDM-5 and mcr-1.1 Escherichia coli phylogroup A isolate associated with patient colonisation in Ireland., PMID:39644970
Structural insights into the advancements of mobile colistin resistance enzymes., PMID:39612773
Site-selective modifications by lipid A phosphoethanolamine transferases linked to colistin resistance and bacterial fitness., PMID:39611852
Overall mutational scanning unveils the essential active residues for the mechanistic action of MCR-1., PMID:39608179
Molecular characterization of colistin-resistant Klebsiella pneumoniae isolates and their conjugative mcr-carrying plasmids., PMID:39566127
Distribution of disinfectant resistant genes in mcr-1-carrying Escherichia coli isolated from children in southern China., PMID:39551109
Prevalence, transmission and genomic epidemiology of mcr-1-positive colistin-resistant Escherichia coli strains isolated from international airplane waste, local resident fecal and wastewater treatment plants., PMID:39547379
Antibiotic resistance genes, colistin-resistant Escherichia coli, and physicochemicals in health care wastewater in Vinh Long General Hospital, Vietnam., PMID:39528737
Sequence variation in the active site of mobile colistin resistance proteins is evolutionarily accommodated through inter-domain interactions., PMID:39509206
Steady existence of Escherichia coli co-resistant to carbapenem and colistin in an animal breeding area even after the colistin forbidden., PMID:39488963
Acetylshikonin reduces the spread of antibiotic resistance via plasmid conjugation., PMID:39481662
Coexistence and genomics characterization of mcr-1 and extended-spectrum-β-lactamase-producing Escherichia coli, an emerging extensively drug-resistant bacteria from sheep in China., PMID:39426540
Mobile genetic elements contributing to horizontal gene transfer of blaNDM among Escherichia coli in the community setting., PMID:39368562
Global distribution and genomic characteristics analysis of avian-derived mcr-1-positive Escherichia coli., PMID:39353372
Risk factors and molecular characterization of carbapenem resistant Escherichia coli recovered from a tertiary hospital in Fujian, China from 2021 to 2023., PMID:39342086
Mechanism of synergistic action of colistin with resveratrol and baicalin against mcr-1-positive Escherichia coli., PMID:39332187
Molecular Epidemiology of mcr-1-Positive Polymyxin B-Resistant Escherichia coli Producing Extended-Spectrum β-Lactamase (ESBL) in a Tertiary Hospital in Shandong, China., PMID:39268958
Convergence of mcr-1 and broad-spectrum β-lactamase genes in Escherichia coli strains from the environmental sector., PMID:39260544
High-throughput screening identification of apigenin that reverses the colistin resistance of mcr-1-positive pathogens., PMID:39248524
For research use only. Not for human or drug use.
