Anti-Influenza A virus RNA polymerase complex Nanobody (SAA1427)

Catalog No.

RVV24101

Expression system

Mammalian Cells

Species reactivity

Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60)) (Influenza A virus (strain A/NT/60/1968 H3N2)) (P03434 & P03432), Influenza A virus (A/Northern Territory/60/1968(H3N2)) (Q1AR05 & Q910D6)

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clonality

Monoclonal

Target

Polymerase acidic protein, 3.1.-.-, RNA-directed RNA polymerase subunit P2, PA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P03434

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1427

The evaluation of DNA-linked inhibitor antibody and AlphaScreen assays for high-throughput screening of compounds targeting the cap-binding domain in influenza a polymerase., PMID:39674552

Identification of B-cell epitopes located on the surface in the PB2 protein of the H9N2 subtype avian influenza virus., PMID:38563198

Characterization of neurotropic HPAI H5N1 viruses with novel genome constellations and mammalian adaptive mutations in free-living mesocarnivores in Canada., PMID:36880345

New Micro-amount of Virion Enrichment Technique (MiVET) to detect influenza A virus in the duck faeces., PMID:30267611

Mechanism of Action of the Anti-Influenza Virus Active Kampo (Traditional Japanese Herbal) Medicine, Hochuekkito., PMID:29275416

[Preparation and detection of anti-influenza A virus polymerase basic protein 1 polyclonal antibody]., PMID:27363203

Codon Deletions in the Influenza A Virus PA Gene Generate Temperature-Sensitive Viruses., PMID:26792748

Progress on adenovirus-vectored universal influenza vaccines., PMID:25876176

Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation., PMID:25855727

Rapid emergence of a PB2-E627K substitution confers a virulent phenotype to an H9N2 avian influenza virus during adoption in mice., PMID:25782865

Influenza a virus assembly intermediates fuse in the cytoplasm., PMID:24603687

Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection., PMID:24567377

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs., PMID:24550300

Resistance to influenza A virus infection in transformed cell lines expressing an anti-PB2 monoclonal antibody., PMID:24140339

Airborne transmission of influenza A/H5N1 virus between ferrets., PMID:22723413

Molecular interactions and trafficking of influenza A virus polymerase proteins analyzed by specific monoclonal antibodies., PMID:22325937

Apical transport of influenza A virus ribonucleoprotein requires Rab11-positive recycling endosome., PMID:21731653

"Boom" and "Bust" cycles in virus growth suggest multiple selective forces in influenza a evolution., PMID:21501520

Influenza virus assays based on virus-inducible reporter cell lines., PMID:21462401

Avian Influenza A virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infection., PMID:19019950

Human monoclonal single chain antibodies (HuScFv) that bind to the polymerase proteins of influenza A virus., PMID:18595527

[Complex environmental and virological monitoring in the Primorye Territory in 2003-2006]., PMID:18041224

Visualization of microtubule-mediated transport of influenza viral progeny ribonucleoprotein., PMID:17905627

Virus-inducible reporter genes as a tool for detecting and quantifying influenza A virus replication., PMID:15847914

Mapping of functional domains on the influenza A virus RNA polymerase PB2 molecule using monoclonal antibodies., PMID:11043953

Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites., PMID:8794308

Influenza A virus RNA polymerase subunit PB2 is the endonuclease which cleaves host cell mRNA and functions only as the trimeric enzyme., PMID:11831724

NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoprotein., PMID:7831767

Transcription of a recombinant influenza virus RNA in cells that can express the influenza virus RNA polymerase and nucleoprotein genes., PMID:1607855

Composition of the helical internal components of influenza virus as revealed by immunogold labeling/electron microscopy., PMID:1727605

Purification and molecular structure of RNA polymerase from influenza virus A/PR8., PMID:2358436

IgG-neutralized influenza virus undergoes primary, but not secondary uncoating in vivo., PMID:2769231

Interaction between anti-influenza viral polymerase antibodies and RNP particles using the in vitro transcription process and an immunogold labelling technique., PMID:2904734

Intracellular localization of the viral polymerase proteins in cells infected with influenza virus and cells expressing PB1 protein from cloned cDNA., PMID:2438429

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