Catalog No.
YHB98602
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys19-His317
Predicted molecular weight
52.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02649
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Apo-E, Apolipoprotein E, APOE, APOE4
Impact of APOE4-related dementia risk in underrepresented groups from the All of Us research program., PMID:40501118
Perceptual discrimination of complex objects: Apolipoprotein E e4 gene-dose effects in mid-life., PMID:40492513
Association of Alzheimer's disease concerns with amyloid burden and lifestyle behaviors in cognitively unimpaired older adults., PMID:40476544
Alzheimer's disease plasma biomarkers in the Midwestern Amish., PMID:40465679
Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype., PMID:40457456
Spatial navigation deficits in early Alzheimer's disease: the role of biomarkers and APOE genotype., PMID:40456910
APOE4 reshapes the lipid droplet proteome and modulates microglial inflammatory responses., PMID:40451545
Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE-Tau Axis via Human Cerebral Organoids with Immuno-SERS., PMID:40444455
Predicting and preventing Alzheimer's disease., PMID:40440380
Depressive symptoms interact with CSF levels of p-tau in predicting cognitive performance in the early stages of Parkinson's disease., PMID:40435794
Semiparametric joint modeling for biomarker trajectory before disease onset., PMID:40433774
Shorter Telomere Length in Individuals with Neurocognitive Disorder and APOE ε4 Genotype., PMID:40429722
Association of Peak Width of Skeletonized Mean Diffusivity With Neurofilament Light Chain in Non-Dementia Adults., PMID:40420623
Whole-genome sequencing analyses suggest novel genetic factors associated with Alzheimer's disease and a cumulative effects model for risk liability., PMID:40419521
The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease., PMID:40419479
Blood-brain barrier permeability varies by brain region and APOE4 status and correlates with brain microstructure among high-AD risk groups., PMID:40409050
Development of a Japanese polygenic risk score model for amyloid-β PET imaging in Alzheimer's disease., PMID:40405310
Anti-Amyloid Agents: A Self-Fulfilling prophecy., PMID:40393205
Age-dependent interactions of APOE isoform 4 and Alzheimer's disease neuropathology: findings from the NACC., PMID:40382659
Association between diffusion MRI-based measures of neurite microstructure and risk of Alzheimer's disease., PMID:40378932
Astrocytic spermidine insufficiency contributes to enhanced pain sensitivity associated with ApoE4., PMID:40375206
The genetic risk factors, molecular pathways, microRNAs, and the gut microbiome in Alzheimer's disease., PMID:40374065
Apolipoprotein E4 facilitates transfection of human monocyte-derived dendritic cells by lipid nanoparticles., PMID:40360096
Increased sedentary behavior is associated with neurodegeneration and worse cognition in older adults over a 7-year period despite high levels of physical activity., PMID:40357887
Relationship between use of anti-platelet agents, oral anti-coagulants, and Aβ burden with cerebral microhemorrhages in cognitively asymptomatic adults., PMID:40356042
Hypothalamic volume, sleep, and APOE genotype in cognitively healthy adults., PMID:40356022
The associations between cerebral microhemorrhages and cognitive decline across Alzheimer's continuum., PMID:40355774
Apolipoprotein E (APOE) and Alzheimer's disease risk in a Ugandan population: A pilot case-control study., PMID:40355218
Role of apolipoprotein E (ApoE) ε4 in cognitive impairment after a stroke: a prospective cohort study., PMID:40349252
Multisystem failure, tipping points, and risk of Alzheimer's disease., PMID:40346724
APOE4 carriers display loss of anticipatory cerebrovascular regulation across the Alzheimer's disease continuum., PMID:40346723
Mediation of the Association Between APOE ε4 Genotype, Cognition, and Dementia by Neuropathology Imaging Markers in the Rotterdam Study., PMID:40344552
APOE4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults., PMID:40332937
Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI., PMID:40328780
The potential utility of arterial spin labeling in predicting brain amyloidosis., PMID:40327919
The fall-dementia connection: Synergistic effects of falls with genetic and health risk factors., PMID:40325974
Comprehensive Clinical and Behavioral Characteristics of Mild Cognitive Impairment According to Amyloid Positivity: A Large Multi-Center Korean Cohort., PMID:40321437
Plasma biomarkers of amyloid, tau & neuroinflammation in Alzheimer's disease and corticobasal syndrome., PMID:40314736
Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease., PMID:40309932
Associations of Accelerated Biological Aging With Dementia and the Mediation Role of Brain Structure: Findings From a Longitudinal Study., PMID:40305743
ApoE4 requires lipidation enhancement to resolve cellular lipid and protein abnormalities following NPC1 inhibition., PMID:40301465
Apolipoprotein E genotypes and amyloid burden associated with cognitive decline in non-demented Parkinson's disease patients: A preliminary analysis., PMID:40300362
Survival Differences Between Individuals With Typical and Atypical Phenotypes of Alzheimer Disease., PMID:40294367
Differential effects of aging, Alzheimer's pathology, and APOE4 on longitudinal functional connectivity and episodic memory in older adults., PMID:40281595
Protein recognition is chiefly mediated by the CDR2 region in TREM2 - an in silico characterization., PMID:40280075
Adherence to life's essential 8 is associated with delayed white matter aging., PMID:40280025
Alzheimer's disease cerebrospinal fluid biomarker levels and APOE genetic status are associated with hippocampal-cerebellar functional connectivity., PMID:40273528
Relationship Between Within-Session Digital Motor Skill Acquisition and Alzheimer Disease Risk Factors Among the MindCrowd Cohort: Cross-Sectional Descriptive Study., PMID:40273338
Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study., PMID:40271551
Discovery of an ApoE4-targeted small-molecule SirT1 enhancer for the treatment of Alzheimer's disease., PMID:40269061
For research use only. Not for human or drug use.
