Catalog No.
PHA13601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NR5A2 (Ser300-Ala541).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Liver receptor homolog 1, hB1F, NR5A2, Alpha-1-fetoprotein transcription factor, CYP7A promoter-binding factor, B1-binding factor, FTF, Nuclear receptor subfamily 5 group A member 2, LRH-1, B1F, CPF, Hepatocytic transcription factor
Purification
Purified by antigen affinity column.
Accession
O00482
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Abnormal phosphorylation of human LRH1 at Ser510 predicts poor prognosis and promotes cell viability in lung squamous cell carcinoma., PMID:40269773
NR5A2 promotes malignancy progression and mediates the effect of cisplatin in cutaneous squamous cell carcinoma., PMID:38358044
Aberrant phosphorylation of human LRH1 at serine 510 is predictable of hepatocellular carcinoma recurrence., PMID:37285077
Ovarian adult-type granulosa cell tumor concomitant with simple endometrial hyperplasia: a case study with selected immunohistochemistry., PMID:31870196
The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions., PMID:31328159
Effects of Dietary Daidzein Supplementation on Reproductive Performance, Serum Hormones, and Reproductive-Related Genes in Rats., PMID:29899203
Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis., PMID:27376874
Local glucocorticoid production in the mouse lung is induced by immune cell stimulation., PMID:22111694
Electrochemiluminescence of peroxydisulfate enhanced by L-cysteine film for sensitive immunoassay., PMID:21239162
Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression., PMID:20734354
Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1., PMID:20483916
Sox9a regulation of ff1a in zebrafish (Danio rerio) suggests an involvement of ff1a in cartilage development., PMID:18950725
MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1., PMID:17916804
Differential expression of steroidogenic factor-1 and FTF/LRH-1 in the rodent ovary., PMID:12865342