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Anti-DPYD Polyclonal Antibody

Catalog #:   PHG32101 Specific References (12) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q12882
Overview

Catalog No.

PHG32101

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DPYD (Ile781-Cys1025).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Dihydropyrimidine dehydrogenase [NADP(+)], DPYD, DPD, Dihydrouracil dehydrogenase, Dihydrothymine dehydrogenase, DHPDHase

Purification

Purified by antigen affinity column.

Accession

Q12882

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with DPYD antibody (PHG32101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 29 kDa
    Observed MW: 29 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with DPYD antibody (PHG32101) at 1 μg/ml.

    Lane 1: HEK293T

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 111 kDa
    Observed MW: 111 kDa
  • Immunohistochemical
    Immunohistochemical analysis of mouse lung tissue stained for DPYD with PHG32101.
References

Case report: Chemotherapy plus sintilimab for the treatment of gastroesophageal junction hepatoid adenocarcinoma with liver metastasis: a case study with literature review., PMID:39931054

Pharmacogenetics Role of Genetic Variants in Immune-Related Factors: A Systematic Review Focusing on mCRC., PMID:36432658

Modern developments in germline pharmacogenomics for oncology prescribing., PMID:35302652

Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer., PMID:32847480

Anti-TSNARE1 IgG plasma levels differ by sex in patients with schizophrenia in a Chinese population., PMID:31336035

Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy., PMID:30114658

Study of Novel Autoantibodies in Schizophrenia., PMID:29373732

Genotypes Affecting the Pharmacokinetics of Anticancer Drugs., PMID:27641154

Uncommon dihydropyrimidine dehydrogenase mutations and toxicity by fluoropyrimidines: a lethal case with a new variant., PMID:26651493

Changes in expression levels of ERCC1, DPYD, and VEGFA mRNA after first-line chemotherapy of metastatic colorectal cancer: results of a multicenter study., PMID:26372896

The monoclonal antibody CH12 augments 5-fluorouracil-induced growth suppression of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III., PMID:24007863

Pharmacogenetics in chemotherapy of colorectal cancer., PMID:19414151

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-DPYD Polyclonal Antibody [PHG32101]
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