Catalog No.
PHG33701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD148/PTPRJ (Arg997-Ala1337).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1
Purification
Purified by antigen affinity column.
Accession
Q12913
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Relieving platelet inhibition using a novel bi-specific antibody: A novel approach for circumventing the platelet storage lesion., PMID:40166144
CD148 agonistic antibody alleviates renal injury induced by chronic angiotensin II infusion in mice., PMID:40165104
A phosphatase-recruiting bispecific antibody-aptamer chimera for enhanced suppression of tumor growth., PMID:37170857
Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts., PMID:35181688
A high-resolution mass spectrometry based proteomic dataset of human regulatory T cells., PMID:34950757
Agonistic anti-CD148 monoclonal antibody attenuates diabetic nephropathy in mice., PMID:31984788
Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?, PMID:29498714
Positive Regulation of Lyn Kinase by CD148 Is Required for B Cell Receptor Signaling in B1 but Not B2 B Cells., PMID:27889108
Risk factors for heparin-induced thrombocytopenia: Focus on Fcγ receptors., PMID:27358188
The mycotoxin patulin decreases expression of density-enhanced phosphatase-1 by down-regulating PPARγ in human colon cancer cells., PMID:25098256
Cogan's syndrome--clinical guidelines and novel therapeutic approaches., PMID:24385257
Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia., PMID:24289109
Identification of autoantibodies against inner ear antigens in a cohort of children with idiopathic sensorineural hearing loss., PMID:23944678
Association of the protein-tyrosine phosphatase DEP-1 with its substrate FLT3 visualized by in situ proximity ligation assay., PMID:23650535
Dominant role of the protein-tyrosine phosphatase CD148 in regulating platelet activation relative to protein-tyrosine phosphatase-1B., PMID:23065825
Tyrosine phosphorylation of DEP-1/CD148 as a mechanism controlling Src kinase activation, endothelial cell permeability, invasion, and capillary formation., PMID:22898603
Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia., PMID:22677127
Protein tyrosine phosphatases in lymphocyte activation and autoimmunity., PMID:22513334
Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival., PMID:22135465
Retinal angiomatosis and cystoid macular oedema in Cogan's syndrome., PMID:21873927
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012
Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase., PMID:19457934
Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis., PMID:19413345
CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages., PMID:19268662
Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling., PMID:18249142
A monoclonal antibody against CD148, a receptor-like tyrosine phosphatase, inhibits endothelial-cell growth and angiogenesis., PMID:16597593
Sensori-neural deafness and hypothyroidism: autoimmunity causing 'pseudo-Pendred syndrome'., PMID:16582570
The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling., PMID:12913111
Antigenic profile of human thymus in concurrence with "Clusters of Thymic Epithelial Staining" classification., PMID:12725440
Autoantibodies to inner ear and endothelial antigens in Cogan's syndrome., PMID:12354474
Novel molecular mechanisms of dendritic cell-induced T cell activation., PMID:10882417
Identification of functional human splenic memory B cells by expression of CD148 and CD27., PMID:9802981
From sentinel to messenger: an extended phenotypic analysis of the monocyte to dendritic cell transition., PMID:9767444
CD148: a receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation., PMID:9759839
CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes., PMID:9531590
Functional characterization of receptor-type protein tyrosine phosphatase CD148 (HPTP eta/DEP-1) in Fc gamma receptor IIa signal transduction of human neutrophils., PMID:9464844
Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta., PMID:7994032
Activation of the interleukin 2 pathway precedes CD3-T cell receptor expression in thymic development. Differential growth requirements of early and mature intrathymic subpopulations., PMID:2522051
For research use only. Not for human or drug use.
