Catalog No.
FHC34410
Species reactivity
Human
Host species
Human
Isotype
VHH-hFc
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor
Concentration
2.22 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P08588
Applications
ELISA, FCM
Form
Liquid
Storage buffer
9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, pH 6.5.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
6B9
Autoimmune Antibodies in Orthostatic Intolerance Syndromes., PMID:40432440
Epac1 participates in β1-adrenoreceptor autoantibody-mediated decreased autophagic flux in cardiomyocytes., PMID:37315585
β1-adrenergic and Muscarinic Acetylcholine Type 2 Receptor Antibodies are Increased in Graves' Hyperthyroidism and Decrease During Antithyroid Therapy., PMID:33434937
Autoantibodies against M5-muscarinic and beta1-adrenergic receptors in periodontitis patients., PMID:32857064
β1 adrenoceptor antibodies induce myocardial apoptosis via inhibiting PGC-1α-related pathway., PMID:32503464
Endoplasmic reticulum stress contributed to β1-adrenoceptor autoantibody-induced reduction of autophagy in cardiomyocytes., PMID:31553425
Anti-ß1-Adrenoreceptor auto-Antibodies in elderly heart failure patients., PMID:30844728
Autoantibody against β1-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4+ T cells by up-regulating AMPK-mediated fatty acid oxidation., PMID:30770790
Activation of T Lymphocytes as a Novel Mechanism in Beta1-Adrenergic Receptor Autoantibody-Induced Cardiac Remodeling., PMID:30747396
β2-adrenergic receptor autoantibodies alleviated myocardial damage induced by β1-adrenergic receptor autoantibodies in heart failure., PMID:29746700
Difference between beta1-adrenoceptor autoantibodies of human and animal origin-Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology., PMID:29425252
Strategy for Identification of Phosphorylation Levels of Low Abundance Proteins in Vivo for Which Antibodies Are not Available., PMID:29367546
Antiadrenergic autoimmunity in postural tachycardia syndrome., PMID:27702852
Immunoadsorption can improve cardiac function in transplant candidates with non-ischemic dilated cardiomyopathy associated with diabetes mellitus., PMID:25936316
Elevated M2-muscarinic and β1-adrenergic receptor autoantibody levels are associated with paroxysmal atrial fibrillation., PMID:25351416
Autoimmune basis for postural tachycardia syndrome., PMID:24572257
β1-Adrenoceptor mRNA level reveals distinctions between infantile hemangioma and vascular malformations., PMID:23370410
Propranolol accelerates adipogenesis in hemangioma stem cells and causes apoptosis of hemangioma endothelial cells., PMID:23096601
Anti-β-adrenoceptors autoimmunity causing 'idiopathic' arrhythmias and cardiomyopathy., PMID:22447021
Beta-adrenergic signals regulate cardiac differentiation of mouse embryonic stem cells via mitogen-activated protein kinase pathways., PMID:21711454
Interleukin-6-deficient mice resist development of experimental autoimmune cardiomyopathy induced by immunization of β1-adrenergic receptor., PMID:21334079
Role for vitamin D receptor in the neuronal control of the hematopoietic stem cell niche., PMID:20813899