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Research Grade Bectumomab (DHD38504)

Host species:Mouse
Isotype:Fab'-G2a-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHD38504

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Mouse

Isotype

Fab'-G2a-kappa

Clonality

Monoclonal

Target

Sialic acid-binding Ig-like lectin 2, Siglec-2, CD22, T-cell surface antigen Leu-14, BL-CAM, SIGLEC2, B-lymphocyte cell adhesion molecule, B-cell receptor CD22

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P20273

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

99mTc-IMMU-LL2, CAS: 158318-63-9

Clone ID

Bectumomab

Data Image
References

Radioimmunoscintigraphy (RIS) with bectumomab (Tc99m labeled IMMU-LL2, Lymphoscan) in the assessment of recurrent non-Hodgkin's lymphoma (NHL), PMID: 12537673

Internalization and intracellular processing of an anti-B-cell lymphoma monoclonal antibody, LL2, PMID: 8112889

Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma, PMID: 11154233

Conjugation of an anti-B-cell lymphoma monoclonal antibody, LL2, to long-circulating drug-carrier lipid emulsions, PMID: 10579680

Pseudomonas exotoxin-based immunotoxins containing the antibody LL2 or LL2-Fab' induce regression of subcutaneous human B-cell lymphoma in mice, PMID: 8428363

Lymphoma imaging with a new technetium-99m labelled antibody, LL2, PMID: 1618230

Clinical utility of radioimmunoscintigraphy of non-Hodgkin's lymphoma with radiolabelled LL2 monoclonal antibody, LymphoSCAN: preliminary results, PMID: 7571023

Initial clinical results with technetium-99m-labeled LL2 monoclonal antibody fragment in the radioimmunodetection of B-cell lymphomas, PMID: 8306276

Datasheet

Document Download

Research Grade Bectumomab.pdf

 

$ 426
Product specifications
100 μg 426 1 mg 1704

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Bectumomab [DHD38504]
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