Research Grade Enokizumab (DHD09601)

Catalog No.

DHD09601

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P15248

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

7F3com-2H2, MEDI-528, CAS: 909875-08-7

Clone ID

Enokizumab

A randomized, controlled trial to evaluate the effect of an anti-interleukin-9 monoclonal antibody in adults with uncontrolled asthma, PMID: 24050312

Biology of the interleukin-9 pathway and its therapeutic potential for the treatment of asthma, PMID: 21428906

MEDI-528, an anti-IL-9 humanized antibody for the treatment of asthma, PMID: 20373267

Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma, PMID: 21356110

Two first-in-human, open-label, phase I dose-escalation safety trials of MEDI-528, a monoclonal antibody against interleukin-9, in healthy adult volunteers, PMID: 19446146

Document Download

Research Grade Enokizumab.pdf