Catalog No.
RHE35901
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
Caspase-3, CPP-32, CPP32, CASP-3, SREBP cleavage activity 1, CASP3, Apopain, SCA-1, Cysteine protease CPP32, Protein Yama
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P42574
Applications
ELISA, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1223
Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application., PMID:39327452
TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer., PMID:37932752
Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling., PMID:34263724
RIG-I activation is critical for responsiveness to checkpoint blockade., PMID:31519811
Evaluation of cellular and transcriptional targeting of breast cancer stem cells via anti-HER2 nanobody conjugated PAMAM dendrimers., PMID:30246563
Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction., PMID:25484045
Combined MUC1-specific nanobody-tagged PEG-polyethylenimine polyplex targeting and transcriptional targeting of tBid transgene for directed killing of MUC1 over-expressing tumour cells., PMID:21704663
Isolation and functional characterization of single domain antibody modulators of Caspase-3 and apoptosis., PMID:18553063