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Anti-Human CASP3/Caspase-3 Nanobody (SAA1223)

Catalog #:   RHE35901 Specific References (8) DATASHEET
Host species: Alpaca
Isotype: VHH-8His-Cys-tag
Applications: ELISA, IF
Expression system: Mammalian Cells
Overview

Catalog No.

RHE35901

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clonality

Monoclonal

Target

Caspase-3, CPP-32, CPP32, CASP-3, SREBP cleavage activity 1, CASP3, Apopain, SCA-1, Cysteine protease CPP32, Protein Yama

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P42574

Applications

ELISA, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1223

Data Image
  • SDS-PAGE
    SDS PAGE for Human CASP3/Caspase-3 Nanobody
References

Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application., PMID:39327452

TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer., PMID:37932752

Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling., PMID:34263724

RIG-I activation is critical for responsiveness to checkpoint blockade., PMID:31519811

Evaluation of cellular and transcriptional targeting of breast cancer stem cells via anti-HER2 nanobody conjugated PAMAM dendrimers., PMID:30246563

Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction., PMID:25484045

Combined MUC1-specific nanobody-tagged PEG-polyethylenimine polyplex targeting and transcriptional targeting of tBid transgene for directed killing of MUC1 over-expressing tumour cells., PMID:21704663

Isolation and functional characterization of single domain antibody modulators of Caspase-3 and apoptosis., PMID:18553063

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human CASP3/Caspase-3 Nanobody (SAA1223) [RHE35901]
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