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Anti-Human GRM5 Nanobody (SAA1086)

Catalog #:   RHE33002 Specific References (50) DATASHEET
Host species: Alpaca
Isotype: VHH-8His-Cys-tag
Applications: ELISA
Expression system: Mammalian Cells
Overview

Catalog No.

RHE33002

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clonality

Monoclonal

Target

GRM5, GPRC1E, mGluR5, MGLUR5, Metabotropic glutamate receptor 5

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P41594

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1086

Data Image
  • SDS-PAGE
    SDS PAGE for Human GRM5 Nanobody
References

Spontaneous partial resolution of autoimmune-mediated brain MRI abnormalities before immunotherapy in anti-metabotropic glutamate receptor 5 encephalitis: a case report., PMID:40519912

Anti-metabotropic glutamate receptor 5 coexistent anti-N-methyl-D-aspartate receptor encephalitis: a case report and literature review., PMID:40028323

Overlapping syndrome of anti-MOG antibody-associated disease and anti-mGluR5 encephalitis manifested as optic neuritis: A case report., PMID:39151524

Encephalitis associated with anti-mGluR5 antibodies., PMID:38423754

Human Metabotropic Glutamate Receptor 5 Antibodies Alter Receptor Levels and Behavior in Mice., PMID:35373379

Metabotropic glutamate type 5 receptor binding availability during dextroamphetamine sensitization in mice and humans., PMID:32559027

Neuroreceptor kinetics in rats repeatedly exposed to quinpirole as a model for OCD., PMID:30845202

Encephalitis Associated to Metabotropic Glutamate Receptor 5 (mGluR5) Antibodies in Cerebrospinal Fluid., PMID:30455705

Spinal RNF20-Mediated Histone H2B Monoubiquitylation Regulates mGluR5 Transcription for Neuropathic Allodynia., PMID:30201771

Encephalitis with mGluR5 antibodies: Symptoms and antibody effects., PMID:29703767

A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma., PMID:28892521

Cocaine self-administration, extinction training and drug-induced relapse change metabotropic glutamate mGlu5 receptors expression: Evidence from radioligand binding and immunohistochemistry assays., PMID:27871824

Immunoadsorption or plasma exchange in the treatment of autoimmune encephalitis: a pilot study., PMID:27604620

Onconeural Antibodies in Acute Psychiatric Inpatient Care., PMID:27578448

Blockade of metabotropic glutamate receptor 5 protects against DNA damage in a rotenone-induced Parkinson's disease model., PMID:26454081

Metabotropic glutamate receptor 5 modulates calcium oscillation and innate immune response induced by lipopolysaccharide in microglial cell., PMID:25250840

Limbic encephalitis with mGluR5 antibodies and immunotherapy-responsive prosopagnosia., PMID:25194012

Seroprevalence of autoantibodies against brain antigens in health and disease., PMID:24853231

Autoimmune encephalitis as differential diagnosis of infectious encephalitis., PMID:24792345

Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission., PMID:24259569

The increased expression of metabotropic glutamate receptor 5 in subventricular zone neural progenitor cells and enhanced neurogenesis in a rat model of intracerebral hemorrhage., PMID:22198019

Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons., PMID:22155385

Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome., PMID:22013185

Group I mGluR-regulated translation of the neuronal glutamate transporter, excitatory amino acid carrier 1., PMID:21371038

Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures., PMID:20413855

The role of metabotropic glutamate receptor 5 in developmental lead neurotoxicity., PMID:19747533

Expression of metabotropic glutamate receptor mGluR5 in human dental pulp., PMID:19410084

Toponomics analysis of functional interactions of the ubiquitin ligase PAM (Protein Associated with Myc) during spinal nociceptive processing., PMID:18753128

Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors., PMID:17389377

Grm5 expression is not required for the oncogenic role of Grm1 in melanocytes., PMID:16040064

Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on Serine 839 regulates Ca2+ oscillations., PMID:15894802

Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses., PMID:15028757

Expression of metabotropic glutamate receptor group I in rat gustatory papillae., PMID:12898387

Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis., PMID:12805104

Immunohistochemical expressions of mGluR5, P2Y2 receptor, PLC-beta1, and IP3R-I and -II in Merkel cells in rat sinus hair follicles., PMID:12802596

Functional metabotropic glutamate receptors are expressed in oligodendrocyte progenitor cells., PMID:12614345

Tyrosine phosphorylation of the metabotropic glutamate receptor mGluR5 in striatal neurons., PMID:12213270

An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells., PMID:12176012

Metabotropic glutamate and GABA(B) receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells., PMID:11935156

Distribution of metabotropic glutamate receptors in the superior colliculus of the adult rat, ferret and cat., PMID:11927160

Activation of group I metabotropic glutamate receptors produces a direct excitation and disinhibition of GABAergic projection neurons in the substantia nigra pars reticulata., PMID:11549710

Bidirectional regulation of neurite elaboration by alternatively spliced metabotropic glutamate receptor 5 (mGluR5) isoforms., PMID:11414786

Cajal-Retzius cells in early postnatal mouse cortex selectively express functional metabotropic glutamate receptors., PMID:11285012

Upregulation of preprodynorphin and preproenkephalin mRNA expression by selective activation of group I metabotropic glutamate receptors in characterized primary cultures of rat striatal neurons., PMID:11165379

Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy., PMID:10947812

Differential distribution of metabotropic glutamate receptors 1a, 1b, and 5 in the rat spinal cord., PMID:10861520

Metabotropic glutamate receptor protein alterations after traumatic brain injury in rats., PMID:10547098

Group I and II metabotropic glutamate receptor expression in cultured rat spinal cord astrocytes., PMID:10213149

In vivo antinociceptive activity of anti-rat mGluR1 and mGluR5 antibodies in rats., PMID:9559947

Distribution of the metabotropic glutamate receptor subtype mGluR5 in rat midbrain periaqueductal grey and relationship with ascending spinofugal afferents., PMID:9197273

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Human GRM5 Nanobody (SAA1086) [RHE33002]
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