Anti-EGR1 Polyclonal Antibody

Catalog No.

PHD28701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human EGR1 (Gln282-Ser433).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Zinc finger protein Krox-24,EGR-1,Nerve growth factor-induced protein A,Early growth response protein 1,NGFI-A,KROX24,Transcription factor ETR103,ZNF225,Transcription factor Zif268,Zinc finger protein 225,EGR1,AT225

Purification

Purified by antigen affinity column.

Accession

P18146

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Deciphering the history of ERK activity from fixed-cell immunofluorescence measurements., PMID:40399273

Synergistic role of gut-microbial L-ornithine in enhancing ustekinumab efficacy for Crohn's disease., PMID:39978335

Abnormal c-Fos expression in TetTag mice containing fos-EGFP., PMID:39741565

Durvalumab and T-DXd Synergistically Promote Apoptosis of Cholangiocarcinoma Cells by Downregulating EGR1 Expression Through Inhibiting P38 MAPK Pathway., PMID:39607471

TLR2-EGR1 signaling axis modulates TGFβ1-induced differentiation of fibroblasts into myofibroblasts in pulmonary fibrosis., PMID:39467355

Molecular mechanism of IgE-mediated FcεRI activation., PMID:39442557

Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway., PMID:38381045

Early growth response 1 as a podocyte injury marker in human glomerular diseases., PMID:38186896

Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer., PMID:37989866

Attenuating Epithelial-to-Mesenchymal Transition in Cancer through Angiopoietin-Like 4 Inhibition in a 3D Tumor Microenvironment Model., PMID:37987244

Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair., PMID:37978868

Molecular Signatures in Swine Innate and Adaptive Immune Responses to African Swine Fever Virus Antigens p30/p54/CD2v Expressed Using a Highly Efficient Semliki Forest Virus Replicon System., PMID:37298266

Hodgkin Lymphoma Cell Lines and Tissues Express mGluR5: A Potential Link to Ophelia Syndrome and Paraneoplastic Neurological Disease., PMID:36831273

The role of tribbles homolog 2 in vascular smooth muscle cell proliferation., PMID:36626273

EGFR is a master switch between immunosuppressive and immunoactive tumor microenvironment in inflammatory breast cancer., PMID:36525493

Fibulin7 aggravates calcium oxalate-induced acute kidney injury by binding to calcium oxalate crystals., PMID:36370444

Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis., PMID:36335669

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression., PMID:36325910

Neuroprotective effects of ergosterol against TNF-α-induced HT-22 hippocampal cell injury., PMID:36030584

Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models., PMID:35951441

Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease., PMID:35693817

Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis., PMID:35543875

Antibody Protection against Long-Term Memory Loss Induced by Monomeric C-Reactive Protein in a Mouse Model of Dementia., PMID:34356892

Inhibition of c-Fos expression attenuates IgE-mediated mast cell activation and allergic inflammation by counteracting an inhibitory AP1/Egr1/IL-4 axis., PMID:34130714

Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia., PMID:33833385

The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury., PMID:33717177

Single cell epigenetic visualization assay., PMID:33511400

Egr-1 mediates low-dose arecoline induced human oral mucosa fibroblast proliferation via transactivation of Wnt5a expression., PMID:33167868

Cav3.2 overexpression in L4 dorsal root ganglion neurons after L5 spinal nerve cutting involves Egr-1, USP5 and HMGB1 in rats: An emerging signaling pathway for neuropathic pain., PMID:32971090

Calcium Channel Blockers Impair the Antitumor Activity of Anti-CD20 Monoclonal Antibodies by Blocking EGR-1 Induction., PMID:32847969

DAPK3 participates in the mRNA processing of immediate early genes in chronic lymphocytic leukaemia., PMID:32306542

Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs., PMID:32153563

A high sensitivity ZENK monoclonal antibody to map neuronal activity in Aves., PMID:31969617

Bioinformatics Analysis of Potential Key Genes in Trastuzumab-Resistant Gastric Cancer., PMID:31949544

Divergent expression patterns of pituitary gonadotropin subunit and GnRH receptor genes to continuous GnRH in vitro and in vivo., PMID:31882740

Noninvasive Brain Delivery and Efficacy of BDNF to Stimulate Neuroregeneration and Suppression of Disease Relapse in EAE Mice., PMID:31846344

Abcam Monoclonal Egr-1 ab133695 is an effective primary antibody replacement for Santa Cruz sc-189 polyclonal Egr-1 in songbirds., PMID:31844776

Recognition memory reconsolidation requires hippocampal Zif268., PMID:31719567

Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness., PMID:31501409

Localization of the ultraviolet-sensor Opn5m and its effect on myopia-related gene expression in the late-embryonic chick eye., PMID:31463372

High dose of dexamethasone protects against EAE-induced motor deficits but impairs learning/memory in C57BL/6 mice., PMID:31040362

Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis., PMID:30971291

Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial., PMID:30967156

Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway., PMID:30915071

Extracellular signal-regulated kinase-1 phosphorylates early growth response-1 at serine 26., PMID:30711252

Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells., PMID:30642980

Global polysome analysis of normal and injured podocytes., PMID:30379099

Non-visual exploration of novel objects increases the levels of plasticity factors in the rat primary visual cortex., PMID:30370183

Egr-1 transactivates WNT5A gene expression to inhibit glucose-induced β-cell proliferation., PMID:30025875

Arsenite-induced histone H3 modification and its effects on EGR1 and FOS expression in HeLa cells., PMID:29350772

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