Catalog No.
RHC86602
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, ITGAM, CD11b, CD11 antigen-like family member B, Integrin alpha-M, CR3A, CD11B, Neutrophil adherence receptor
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P11215
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1302
Reprogramming tumor microenvironment with precise photothermal therapy by calreticulin nanobody-engineered probiotics., PMID:39303415
Multiparametric Immunoimaging Maps Inflammatory Signatures in Murine Myocardial Infarction Models., PMID:37547068
Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2., PMID:35738398
Combination therapy with Nab-paclitaxel and the interleukin-15 fused with anti-human serum albumin nanobody as a synergistic treatment for colorectal cancer., PMID:35019820
Employing nanobodies for immune landscape profiling by PET imaging in mice., PMID:33899016
Oncolytic herpesvirus expressing PD-L1 BiTE for cancer therapy: exploiting tumor immune suppression as an opportunity for targeted immunotherapy., PMID:33820820
Tumor necrosis factor α inhibition overcomes immunosuppressive M2b macrophage-induced bevacizumab resistance in triple-negative breast cancer., PMID:33214550
Sortase-A mediated chemoenzymatic lipidation of single-domain antibodies for cell membrane engineering., PMID:32473290
Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade., PMID:31375632
Sortagging of liposomes with a murine CD11b-specific VHH increases in vitro and in vivo targeting specificity of myeloid cells., PMID:30468837
Sortaggable liposomes: Evaluation of reaction conditions for single-domain antibody conjugation by Sortase-A and targeting of CD11b+ myeloid cells., PMID:30266669
Nanobody-Antigen Conjugates Elicit HPV-Specific Antitumor Immune Responses., PMID:29792298
Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1-Specific VHHs., PMID:29459478
The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent., PMID:29263417
Generation of Immunity against Pathogens via Single-Domain Antibody-Antigen Constructs., PMID:27821668
Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis., PMID:27339464
Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics., PMID:26630549
Increasing the potency of neutralizing single-domain antibodies by functionalization with a CD11b/CD18 binding domain., PMID:26192995
Noninvasive imaging of immune responses., PMID:25902531
Streamlined method for parallel identification of single domain antibodies to membrane receptors on whole cells., PMID:25819371
Monitoring liver macrophages using nanobodies targeting Vsig4: concanavalin A induced acute hepatitis as paradigm., PMID:25440182
SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis., PMID:23447654
For research use only. Not for human or drug use.
