Catalog No.
RHC44601
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
FUR, PCSK3, PACE, FURIN, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, Furin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P09958
Applications
ELISA, IP, SPR
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1180
Targeting intracellular cancer proteins with tumor-microenvironment-responsive bispecific nanobody-PROTACs for enhanced therapeutic efficacy., PMID:39830023
Novel Anti-Mesothelin Nanobodies and Recombinant Immunotoxins with Pseudomonas Exotoxin Catalytic Domain for Cancer Therapeutics., PMID:38052492
Impact of new variants on SARS-CoV-2 infectivity and neutralization: A molecular assessment of the alterations in the spike-host protein interactions., PMID:35194576
The role of gelsolin domain 3 in familial amyloidosis (Finnish type)., PMID:31243148
Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant., PMID:30625383
Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity., PMID:29581296
AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model., PMID:28334940
Non-Invasive Imaging of Amyloid Deposits in a Mouse Model of AGel Using 99mTc-Modified Nanobodies and SPECT/CT., PMID:27130233
An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model., PMID:25601851
Chaperone nanobodies protect gelsolin against MT1-MMP degradation and alleviate amyloid burden in the gelsolin amyloidosis mouse model., PMID:25023329
Generation and characterization of non-competitive furin-inhibiting nanobodies., PMID:22920187
For research use only. Not for human or drug use.
