Catalog No.
RHB89901
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
C3, ASP, Complement C3, C3adesArg, C3bc, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P01024
Applications
ELISA, SPR
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1166
Differences in complement activation of serum-resistant and serum-sensitive Klebsiella pneumoniae isolates., PMID:40424786
Insights into the recognition mechanism of shark-derived single-domain antibodies with high affinity and specificity targeting fluoroquinolones., PMID:40417246
[Enriching plasma exosomes for proteomic analysis using a phosphatidylserine-imprinted polymer]., PMID:40331617
Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein., PMID:39885527
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring., PMID:39849196
Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration., PMID:39397258
The Thermodynamic Fingerprints of Ultra-Tight Nanobody-Antigen Binding Probed via Two-Color Single-Molecule Coincidence Detection., PMID:38003569
A nanobody-based complement inhibitor targeting complement component 2 reduces hemolysis in a complement humanized mouse model of autoimmune hemolytic anemia., PMID:37315680
VH-Based Mini Q-Body: A Novel Quench-Based Immunosensor., PMID:36850849
A Novel Electrochemiluminescence Immunosensor Based on Resonance Energy Transfer between g-CN and NU-1000(Zr) for Ultrasensitive Detection of Ochratoxin A in Coffee., PMID:36832782
Nanobody-mediated complement activation to kill HIV-infected cells., PMID:36799046
Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement., PMID:36739657
IgNAR characterization and gene loci identification in whitespotted bamboo shark (Chiloscyllium plagiosum) genome., PMID:36649810
Complement killing of clinical Klebsiella pneumoniae isolates is serum concentration dependent., PMID:36336240
Atomically dispersed Mn boosting photoelectrochemical SARS-CoV-2 spike protein immunosensing on carbon nitride., PMID:36213529
Structure determination of an unstable macromolecular complex enabled by nanobody-peptide bridging., PMID:36173177
Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity., PMID:35935935
Development of camelid monoclonal nanobody against SLC39A6 zinc transporter protein., PMID:35432806
Multifaceted Activities of Seven Nanobodies against Complement C4b., PMID:35428691
Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies., PMID:33671302
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity., PMID:32938727
An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase., PMID:32769120
Recruitment of properdin by bi-specific nanobodies activates the alternative pathway of complement., PMID:32599335
Complement activation by human IgG antibodies to galactose-α-1,3-galactose., PMID:32583419
A C3-specific nanobody that blocks all three activation pathways in the human and murine complement system., PMID:32376685
A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement., PMID:29497000
Transglutaminase mediated PEGylation of nanobodies for targeted nano-drug delivery., PMID:32254288
A Single Domain-Based Anti-Her2 Antibody Has Potent Antitumor Activities., PMID:29455083
Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers., PMID:28410210
Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity., PMID:27889311
Selection and characterization of camelid nanobodies towards urokinase-type plasminogen activator., PMID:25749705
Selection and identification of single-domain antibody fragment against capsid protein of porcine circovirus type 2 (PCV2) from C. bactrianus., PMID:24736187
For research use only. Not for human or drug use.
