Catalog No.
PHH07501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PCBP2 (Asn11-Ser173).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2
Purification
Purified by antigen affinity column.
Accession
Q15366
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Crystal structure of a highly conserved enteroviral 5' cloverleaf RNA replication element., PMID:37029118
Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions., PMID:36592411
PCBP2 Is Downregulated in Degenerating Neurons and Rarely Observed in TDP-43-Positive Inclusions in Sporadic Amyotrophic Lateral Sclerosis., PMID:33313661
IRTKS negatively regulates antiviral immunity through PCBP2 sumoylation-mediated MAVS degradation., PMID:26348439
Differential expression of polycytosine-binding protein isoforms in adrenal gland, locus coeruleus and midbrain., PMID:25463520
Specific enrichment of the RNA-binding proteins PCBP1 and PCBP2 in chief cells of the murine gastric mucosa., PMID:24480778
Norovirus genome circularization and efficient replication are facilitated by binding of PCBP2 and hnRNP A1., PMID:23946460
Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome., PMID:21632751
The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation., PMID:18656221
Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo., PMID:12970749
Interaction of poly(rC)-binding protein 2 with the 5'-terminal stem loop of the hepatitis C-virus genome., PMID:11163645
Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA., PMID:9257647
For research use only. Not for human or drug use.
