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Anti-Human STXBP2 Polyclonal Antibody

Catalog #:   PHH21201 Specific References (11) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q15833
Overview

Catalog No.

PHH21201

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human STXBP2 (Met1-Arg490).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

UNC18B, Unc18-2, STXBP2, Protein unc-18 homolog B, Unc-18B, Protein unc-18 homolog 2, Syntaxin-binding protein 2

Purification

Purified by antigen affinity column.

Accession

Q15833

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with STXBP2 antibody (PHH21201) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 57 kDa
    Observed MW: 57 kDa
References

Novel Molecular Therapies and Genetic Landscape in Selected Rare Diseases with Hematologic Manifestations: A Review of the Literature., PMID:36766791

Role of Genetic Polymorphism Present in Macrophage Activation Syndrome Pathway in Post Mortem Biopsies of Patients with COVID-19., PMID:36016321

Neonatal Haemophagocytic Lymphohistiocytosis Associated with Maternal Adult-Onset Still's Disease., PMID:27304999

Late-onset severe chronic active EBV in a patient for five years with mutations in STXBP2 (MUNC18-2) and PRF1 (perforin 1)., PMID:25947952

[Natural killer cell cytotoxic activity in critical pediatric patients with suspected hemophagocytic syndrome]., PMID:25081072

Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation., PMID:23487749

Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases., PMID:20823128

Munc18-syntaxin complexes and exocytosis in human platelets., PMID:12649283

Evidence of a role for Munc18-2 and microtubules in mast cell granule exocytosis., PMID:12482918

Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes., PMID:9677404

Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4., PMID:9045631

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human STXBP2 Polyclonal Antibody [PHH21201]
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