Catalog No.
PHH21201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human STXBP2 (Met1-Arg490).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
UNC18B, Unc18-2, STXBP2, Protein unc-18 homolog B, Unc-18B, Protein unc-18 homolog 2, Syntaxin-binding protein 2
Purification
Purified by antigen affinity column.
Accession
Q15833
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Novel Molecular Therapies and Genetic Landscape in Selected Rare Diseases with Hematologic Manifestations: A Review of the Literature., PMID:36766791
Role of Genetic Polymorphism Present in Macrophage Activation Syndrome Pathway in Post Mortem Biopsies of Patients with COVID-19., PMID:36016321
Neonatal Haemophagocytic Lymphohistiocytosis Associated with Maternal Adult-Onset Still's Disease., PMID:27304999
Late-onset severe chronic active EBV in a patient for five years with mutations in STXBP2 (MUNC18-2) and PRF1 (perforin 1)., PMID:25947952
[Natural killer cell cytotoxic activity in critical pediatric patients with suspected hemophagocytic syndrome]., PMID:25081072
Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation., PMID:23487749
Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases., PMID:20823128
Munc18-syntaxin complexes and exocytosis in human platelets., PMID:12649283
Evidence of a role for Munc18-2 and microtubules in mast cell granule exocytosis., PMID:12482918
Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes., PMID:9677404
Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4., PMID:9045631