Catalog No.
PHG84801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ITIH4 (Gly32-Gly267).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Inter-alpha-trypsin inhibitor family heavy chain-related protein, Inter-alpha-trypsin inhibitor heavy chain H4, PK120, PK-120, Plasma kallikrein sensitive glycoprotein 120, Inter-alpha-inhibitor heavy chain 4, ITIHL1, ITIH4, IHRP, ITI-HC4, ITI heavy chain H4, Gp120
Purification
Purified by antigen affinity column.
Accession
Q14624
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Particulate matter-related ITIH4 deficiency is associated with an emphysema phenotype of chronic obstructive pulmonary disease through JNK-dependent and JNK-independent signaling., PMID:40404214
Potential biomarkers for psoriasis topical treatment by in-depth serum proteomics., PMID:37621164
Validation of new automated turbidimetric immunoassays for the measurement of haptoglobin and inter-α-trypsin inhibitor heavy chain H4 specific for the bovine species., PMID:36328958
The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualizing stimulus define the cells' potential for decidualization success., PMID:34524461
Protease inhibitor plasma concentrations associate with COVID-19 infection., PMID:34458849
A serum proteome signature to predict mortality in severe COVID-19 patients., PMID:34226277
CD5L as an Extracellular Vesicle-Derived Biomarker for Liquid Biopsy of Lung Cancer., PMID:33808296
Citrullinated inter-alpha-trypsin inhibitor heavy chain 4 in arthritic joints and its potential effect in the neutrophil migration., PMID:33238047
Development and validation of an ELISA for the quantification of bovine ITIH4 in serum and milk., PMID:31450165
Elevated levels of circulating ITIH4 are associated with hepatocellular carcinoma with nonalcoholic fatty liver disease: from pig model to human study., PMID:31238892
Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis., PMID:29636082
Purification and determination of C-reactive protein and inter-α-trypsin inhibitor heavy chain 4 in dogs after major surgery through generation of specific antibodies., PMID:27590422
Screening for potential serum biomarkers in rat mesangial proliferative nephritis., PMID:26791873
Inter-α-trypsin inhibitor heavy chain 5 (ITIH5) is overexpressed in inflammatory skin diseases and affects epidermal morphology in constitutive knockout mice and murine 3D skin models., PMID:25809190
Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscan™) platform., PMID:24505114
Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay., PMID:16574760
Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins., PMID:16130172
Classification of cancer types by measuring variants of host response proteins using SELDI serum assays., PMID:15704152
ITIH4 (inter-alpha-trypsin inhibitor heavy chain 4) is a new acute-phase protein isolated from cattle during experimental infection., PMID:15213118
Quantitative measurement of the novel human plasma protein, IHRP, by sandwich ELISA., PMID:11256472
The novel acute phase protein, IHRP, inhibits actin polymerization and phagocytosis of polymorphonuclear cells., PMID:10939621
Purification and characterization of PK-120, a novel substrate for plasma kallikrein, from guinea pig plasma., PMID:7550116
For research use only. Not for human or drug use.
