Catalog No.
PHH38201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PTPRO (Asn916-Val1208).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PTPRO, PTP-U2, PTPase U2, Glomerular epithelial protein 1, Receptor-type tyrosine-protein phosphatase O, R-PTP-O, PTPU2, GLEPP1, Protein tyrosine phosphatase U2
Purification
Purified by antigen affinity column.
Accession
Q16827
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting undruggable phosphatase overcomes trastuzumab resistance by inhibiting multi-oncogenic kinases., PMID:39094301
Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study., PMID:32900843
PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitis., PMID:32373213
Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases., PMID:31616406
Global polysome analysis of normal and injured podocytes., PMID:30379099
The Effect of Cortex/Medulla Proportions on Molecular Diagnoses in Kidney Transplant Biopsies: Rejection and Injury Can Be Assessed in Medulla., PMID:28226404
MiR-17-92 represses PTPROt and PP2A phosphatases and amplifies tonic BCR signaling in DLBCL cells., PMID:27720936
Nature and nurture: a case of transcending haematological pre-malignancies in a pair of monozygotic twins adding possible clues on the pathogenesis of B-cell proliferations., PMID:25752595
A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation., PMID:25273097
Interaction of PTPRO and TLR4 signaling in hepatocellular carcinoma., PMID:25034527
Disruption of PTPRO causes childhood-onset nephrotic syndrome., PMID:21722858
Expression of PTPRO in the interneurons of adult mouse olfactory bulb., PMID:19924828
BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt., PMID:19855081
Antibodies to protein tyrosine phosphatase receptor type O (PTPro) increase glomerular albumin permeability (P(alb))., PMID:19403647
Podocyte injury induced by mesangial-derived cytokines in IgA nephropathy., PMID:18685143
Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation., PMID:16888096
Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat., PMID:11532090
Glomerular laminin isoform transitions: errors in metanephric culture are corrected by grafting., PMID:11249861
Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate., PMID:11086029
Isolation and characterization of murine orthologue of PTP-BK., PMID:11027578
Tubulointerstitial nephritis antigen: an extracellular matrix protein that selectively regulates tubulogenesis vs. glomerulogenesis during mammalian renal development., PMID:10500175
Podocyte phenotypes as defined by expression and distribution of GLEPP1 in the developing glomerulus and in nephrotic glomeruli from MCD, CNF, and FSGS. A dedifferentiation hypothesis for the nephrotic syndrome., PMID:9639039
Glomerular epithelial protein 1 and podocalyxin-like protein 1 in inflammatory glomerular disease (crescentic nephritis) in rabbit and man., PMID:8600307
Molecular cloning of cDNAs encoding human GLEPP1, a membrane protein tyrosine phosphatase: characterization of the GLEPP1 protein distribution in human kidney and assignment of the GLEPP1 gene to human chromosome 12p12-p13., PMID:7665166
GLEPP1, a renal glomerular epithelial cell (podocyte) membrane protein-tyrosine phosphatase. Identification, molecular cloning, and characterization in rabbit., PMID:7519601
For research use only. Not for human or drug use.
