Catalog No.
PHK75401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human USP22 (Gly182-Glu525).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Deubiquitinating enzyme 22, USP22, Ubiquitin thioesterase 22, Ubiquitin carboxyl-terminal hydrolase 22, KIAA1063, USP3L, Ubiquitin-specific-processing protease 22
Purification
Purified by antigen affinity column.
Accession
Q9UPT9
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Demethylzeylasteral induces PD-L1 ubiquitin-proteasome degradation and promotes antitumor immunity via targeting USP22., PMID:39525573
A1BG-AS1 promotes the biological functions of osteosarcoma cells via regulating the microRNA-148a-3p/USP22 axis and stabilizing the expression of SIRT1 through deubiquitinase function., PMID:37747800
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice., PMID:37127227
[Plasma exosomal miR-335-5p serves as a diagnostic indicator and inhibits immune escape in triple-negative breast cancer]., PMID:35583065
Targeted eradication of gastric cancer stem cells by CD44 targeting USP22 small interfering RNA-loaded nanoliposomes., PMID:30543303
Targeting CD26 suppresses proliferation of malignant mesothelioma cell via downmodulation of ubiquitin-specific protease 22., PMID:30197002
Identification of potential target genes of USP22 via ChIP-seq and RNA-seq analysis in HeLa cells., PMID:30088609
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining., PMID:29520062
Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation., PMID:25846153
Ubiquitin-specific peptidase 22 overexpression may promote cancer progression and poor prognosis in human gastric carcinoma., PMID:25445209
Regulation of cancer stem cell properties by CD9 in human B-acute lymphoblastic leukemia., PMID:21549094
For research use only. Not for human or drug use.
