Catalog No.
PHA29701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GNB5 (Met95-Ala395).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Guanine nucleotide-binding protein subunit beta-5, GNB5, Gbeta5, Transducin beta chain 5
Purification
Purified by antigen affinity column.
Accession
O14775
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Modeling therapy resistance via the EGFR signaling pathway., PMID:30892828
Systems analysis identifies potential target genes to overcome cetuximab resistance in colorectal cancer cells., PMID:30719834
A High-Throughput Time-Resolved Fluorescence Energy Transfer Assay to Screen for Modulators of RGS7/Gβ5/R7BP Complex., PMID:29658790
Expression of the Gβ5/R7-RGS protein complex in pituitary and pancreatic islet cells., PMID:22322946
Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein., PMID:20100282
Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites., PMID:19797210
Assays of nuclear localization of R7/Gbeta5 complexes., PMID:15488180
GTPase regulators and photoresponses in cones of the eastern chipmunk., PMID:12598617
Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats., PMID:11886441
Nuclear localization of G protein beta 5 and regulator of G protein signaling 7 in neurons and brain., PMID:11152459
Differential expression of the G protein beta(5) gene: analysis of mouse brain, peripheral tissues, and cultured cell lines., PMID:10854285
RGS7 complex formation and colocalization with the Gbeta5 subunit in the adult rat brain and influence on Gbeta5gamma2-mediated PLCbeta signaling., PMID:10723068
Copurification of brain G-protein beta5 with RGS6 and RGS7., PMID:10648734
Instability of the G-protein beta5 subunit in detergent., PMID:10036171
Immunohistochemical localization of G protein beta1, beta2, beta3, beta4, beta5, and gamma3 subunits in the adult rat brain., PMID:9648884