Catalog No.
PHF17301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human EIF6 (Met1-Thr245).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Eukaryotic translation initiation factor 6, EIF3A, eIF-6, ITGB4BP, B(2)GCN homolog, B4 integrin interactor, CAB, p27(BBP), EIF6
Purification
Purified by antigen affinity column.
Accession
P56537
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Biglycan fragment modulates TGF-β activity in intervertebral disc via an eIF6-coupled intracellular path., PMID:39951526
Dysregulation of Translation Factors EIF2S1, EIF5A and EIF6 in Intestinal-Type Adenocarcinoma (ITAC)., PMID:34830804
circ-EIF6 encodes EIF6-224aa to promote TNBC progression via stabilizing MYH9 and activating the Wnt/beta-catenin pathway., PMID:34450253
Cytoskeletal proteins associate with components of the ribosomal maturation and translation apparatus in Xenopus stage I oocytes., PMID:25230050
Identification of ITGB4BP as a new interaction protein of P311., PMID:22365962
Tagging of functional ribosomes in living cells by HaloTag® technology., PMID:21082278
In X. laevis embryos high levels of the anti-apoptotic factor p27BBP/eIF6 are stage-dependently found in BrdU and TUNEL-reactive territories., PMID:20663234
Nuclear myosin VI enhances RNA polymerase II-dependent transcription., PMID:16949370
Safrole oxide induced human umbilical vein vascular endothelial cell differentiation into neuron-like cells by depressing the reactive oxygen species level at the low concentration., PMID:16473419
Inhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic cocultures., PMID:15159456
Overexpression of p27BBP in head and neck carcinomas and their lymph node metastases., PMID:15122657
Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly., PMID:14654845
The Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis., PMID:11238882
The beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly., PMID:10085284
Molecular cloning and functional expression of a human cDNA encoding translation initiation factor 6., PMID:9405604
Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells., PMID:9374518
For research use only. Not for human or drug use.
