Catalog No.
PHC21601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human POLB (Asn12-Glu335).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DNA polymerase beta, POLB
Purification
Purified by antigen affinity column.
Accession
P06746
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The hematopoietic compartment is sufficient for lupus development resulting from the POLB-Y265C mutation., PMID:35486639
DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model., PMID:34186496
Novel Autoantibodies Related to Cell Death and DNA Repair Pathways in Systemic Lupus Erythematosus., PMID:31494269
HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects., PMID:27500639
The impact of ovarian stimulation on the expression of candidate reprogramming genes in mouse preimplantation embryos., PMID:23154201
A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)., PMID:21857901
Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis., PMID:18006695
Involvement of Escherichia coli DNA polymerase II in response to oxidative damage and adaptive mutation., PMID:7928992
Cloning the polB gene of Escherichia coli and identification of its product., PMID:2684981