Catalog No.
PHJ91101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CYP46A1 (His45-Cys500).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Cholesterol 24-hydroxylase, Cholesterol 24-monooxygenase, CH24H, CYP46A1, Cytochrome P450 46A1, CYP46, Cholesterol 24S-hydroxylase
Purification
Purified by antigen affinity column.
Accession
Q9Y6A2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Recent Progress in the Development of New Antiepileptic Drugs with Novel Targets., PMID:38020406
Cytochrome P450 Family 46 Subfamily A Member 1 Promotes the Progression of Colorectal Cancer by Inducing Tumor Cell Proliferation and Angiogenesis., PMID:37909961
Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization., PMID:30884121
24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development., PMID:27671648
Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer., PMID:27341022
Cortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain., PMID:18729719
Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain., PMID:18241055
For research use only. Not for human or drug use.
