Catalog No.
PHK73201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VAMP8 (Glu2-Lys75).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
VAMP8, EDB, Endobrevin, VAMP-8, Vesicle-associated membrane protein 8
Purification
Purified by antigen affinity column.
Accession
Q9BV40
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets., PMID:31648331
Human Platelet Vesicles Exhibit Distinct Size and Proteome., PMID:28587468
UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs., PMID:24550300
SNAP-23 and syntaxin-3 are required for chemokine release by mature human mast cells., PMID:21981832
Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet α-granules., PMID:21622648
Aspirin regulates SNARE protein expression and phagocytosis in dendritic cells., PMID:21231793
Vesicle-associated membrane protein (VAMP) cleavage by a new metalloprotease from the Brazilian scorpion Tityus serrulatus., PMID:20026600
Expression of antizyme inhibitor 2 in mast cells and role of polyamines as selective regulators of serotonin secretion., PMID:19718454
Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin., PMID:18923845
The regulated exocytosis of enlargeosomes is mediated by a SNARE machinery that includes VAMP4., PMID:18713833
Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells., PMID:18253931
VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways., PMID:18203950
JunB is required for IgE-mediated degranulation and cytokine release of mast cells., PMID:17982078
A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils., PMID:16677249
Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events., PMID:15133481
SNARE expression and localization in renal epithelial cells suggest mechanism for variability of trafficking phenotypes., PMID:12372788
Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells., PMID:11278762
Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic beta cells and its physiological function in exo-endocytosis of secretory granules., PMID:11112705
A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function., PMID:11101518
The R-SNARE endobrevin/VAMP-8 mediates homotypic fusion of early endosomes and late endosomes., PMID:11029036
Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking., PMID:10564279
For research use only. Not for human or drug use.
