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Anti-Human CRHR1 Polyclonal Antibody

Catalog #:   PHE06601 Specific References (34) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P34998
Overview

Catalog No.

PHE06601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CRHR1 (Ser24-Lys113).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CRH-R1, CRHR1, CRFR, CRFR-1, Corticotropin-releasing factor receptor 1, CRFR1, CRF-R1, CRF-R-1, Corticotropin-releasing hormone receptor 1, CRHR, CRH-R-1

Purification

Purified by antigen affinity column.

Accession

P34998

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CRHR1 antibody (PHE06601) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 22 kDa
    Observed MW: 22 kDa
References

Mast cells and corticotropin-releasing hormone receptors in duodenal tissue of children with functional dyspepsia., PMID:40050228

Ascaris exposure and its association with lung function, asthma, and DNA methylation in Northern Europe., PMID:34996616

Stress and Nasal Allergy: Corticotropin-Releasing Hormone Stimulates Mast Cell Degranulation and Proliferation in Human Nasal Mucosa., PMID:33803422

Repeated and single maternal separation specifically alter microglial morphology in the prefrontal cortex and neurogenesis in the hippocampus of 15-day-old male mice., PMID:33165192

IL‑18 knockout alleviates atopic dermatitis‑like skin lesions induced by MC903 in a mouse model., PMID:32626950

Icariin inhibits inflammation via immunomodulation of the cutaneous hypothalamus-pituitary-adrenal axis in vitro., PMID:30155911

Molecular hypotheses to explain the shared pathways and underlying pathobiological causes in catatonia and in catatonic presentations in neuropsychiatric disorders., PMID:29523295

Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response., PMID:29317694

Nur77 gene expression levels were involved in different ACTH-secretion autonomy between Cushing's disease and subclinical Cushing's disease., PMID:27025408

Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome., PMID:26272340

Corticotropin-releasing factor receptor type 1 colocalizes with type 2 in corticotropin-releasing factor-containing cellular profiles in rat brain., PMID:25275258

Presence and distribution of urocortin and its receptors in the epididymis of alpaca (Vicugna pacos)., PMID:24661003

Presence and distribution of urocortin and corticotrophin-releasing hormone receptors in the bovine thyroid gland., PMID:24219151

Alternative mRNA splicing of G protein-coupled receptors., PMID:23332707

Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele., PMID:22886732

Regulation of estradiol and progesterone production by CRH-R1 and -R2 is through divergent signaling pathways in cultured human placental trophoblasts., PMID:22865371

[Expression of secretions of hypothalamus-pituitary-adrenal axis in human hypertrophic scar]., PMID:22340789

Differential regulation of glucose transporters mediated by CRH receptor type 1 and type 2 in human placental trophoblasts., PMID:22234467

Local secretion of urocortin 1 promotes microvascular permeability during lipopolysaccharide-induced inflammation., PMID:19819946

Structural determinants critical for localization and signaling within the seventh transmembrane domain of the type 1 corticotropin releasing hormone receptor: lessons from the receptor variant R1d., PMID:18772229

Corticotropin-releasing hormone stimulates SGK-1 kinase expression in cultured hippocampal neurons via CRH-R1., PMID:18713960

Differential regulation of prostaglandin production mediated by corticotropin-releasing hormone receptor type 1 and type 2 in cultured human placental trophoblasts., PMID:18325997

Intratumoral CRH modulates immuno-escape of ovarian cancer cells through FasL regulation., PMID:17667919

Expression of mRNAs encoding receptors that mediate stress signals in gonadotropin-releasing hormone neurons of the mouse., PMID:16721036

Corticotropin-releasing hormone modulates human trophoblast invasion through carcinoembryonic antigen-related cell adhesion molecule-1 regulation., PMID:16400017

Regulation of corticotropin-releasing hormone receptor-2 expression in human cord blood-derived cultured mast cells., PMID:16326828

mRNA expression profiles for corticotrophin-releasing hormone, urocortin, CRH-binding protein and CRH receptors in human term gestational tissues determined by real-time quantitative RT-PCR., PMID:15072543

Detection of corticotropin-releasing hormone receptors R1 and R2 (CRH-R1, CRH-R2) using fluorescence immunohistochemistry in the myometrium of women delivering preterm or at term., PMID:14650949

Brain region-specific neuroprotective action and signaling of corticotropin-releasing hormone in primary neurons., PMID:12933679

Redistribution of corticotropin-releasing hormone receptor R2 using fluorescence immunohistochemistry in fetal membranes of women delivering preterm or at term., PMID:12635470

Attenuation of corticotropin-releasing hormone and arginine vasopressin responsiveness during late-gestation pregnancy in sheep., PMID:12021066

Detection of corticotropin-releasing hormone receptor 1 immunoreactivity in cholinergic, dopaminergic and noradrenergic neurons of the murine basal forebrain and brainstem nuclei--potential implication for arousal and attention., PMID:11440798

Inhibition of corticotropin releasing hormone type-1 receptor translation by an upstream AUG triplet in the 5' untranslated region., PMID:11179443

Corticotrophin-releasing hormone receptor type 1: generation and characterization of polyclonal antipeptide antibodies and their localization in pituitary cells and cortical neurones in vitro., PMID:8843021

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human CRHR1 Polyclonal Antibody [PHE06601]
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