Catalog No.
PHE35001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human AKR1C3 (Met1-Tyr323).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
3-alpha-hydroxysteroid dehydrogenase type 2, Aldo-keto reductase family 1 member C3, Testosterone 17-beta-dehydrogenase 5, 3-alpha-HSD type II, brain, DD3, DD-3, PGFS, Prostaglandin F synthase, 17-beta-HSD 5, Chlordecone reductase homolog HAKRb, Dihydrodiol dehydrogenase type I, Dihydrodiol dehydrogenase 3, HSD17B5, 17-beta-hydroxysteroid dehydrogenase type 5, HA1753, KIAA0119, DDH1, 3-alpha-HSD type 2, AKR1C3
Purification
Purified by antigen affinity column.
Accession
P42330
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587
Possible New Histological Prognostic Index for Large B-Cell Lymphoma., PMID:37834968
Subclinical rejection-free diagnostic after kidney transplantation using blood gene expression., PMID:36990211
Understanding Protein Protocadherin-19 (PCDH19) Syndrome: A Literature Review of the Pathophysiology., PMID:35822151
AKR1C3 expression in T acute lymphoblastic leukemia/lymphoma for clinical use as a biomarker., PMID:35388063
Prediction of Radioresistant Prostate Cancer Based on Differentially Expressed Proteins., PMID:32791508
Early upregulation of AR and steroidogenesis enzyme expression after 3 months of androgen-deprivation therapy., PMID:32560654
A Mansonone Derivative Coupled with Monoclonal Antibody 4D5-Modified Chitosan Inhibit AKR1C3 to Treat Castration-Resistant Prostate Cancer., PMID:32431503
Early effects of first-line treatment with anti-interleukin-6 receptor antibody tocilizumab for chronic active antibody-mediated rejection in kidney transplantation., PMID:32415711
Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways., PMID:31303763
Characterization of a highly specific monoclonal antibody against human aldo-keto reductase AKR1C3., PMID:30639543
Identification of specific and common diagnostic antibody markers for gastrointestinal cancers by SEREX screening using testis cDNA phage library., PMID:29719626
Canine placental prostaglandin E2 synthase: expression, localization, and biological functions in providing substrates for prepartum PGF2alpha synthesis., PMID:25297547
Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: the role of IL-6 signaling and Nrf2/AKR1C axis identification., PMID:23933386
Biosynthesis and degradation of canine placental prostaglandins: prepartum changes in expression and function of prostaglandin F2α-synthase (PGFS, AKR1C3) and 15-hydroxyprostaglandin dehydrogenase (HPGD)., PMID:23677986
SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer., PMID:23579488
IGF2 increases de novo steroidogenesis in prostate cancer cells., PMID:23319492
Developmental evaluation of aldo-keto reductase 1C3 expression in the cryptorchid testis., PMID:19942269
Expression of enzymes involved in synthesis and metabolism of estradiol in human breast as studied by immunocytochemistry and in situ hybridization., PMID:19130396
Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system., PMID:18574251
Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma., PMID:16601286
Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate., PMID:15582534
For research use only. Not for human or drug use.
