Catalog No.
PHH82501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human AMOT (Thr650-Glu772).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Angiomotin, KIAA1071, AMOT
Purification
Purified by antigen affinity column.
Accession
Q4VCS5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting soluble CD146 with a neutralizing antibody inhibits vascularization, growth and survival of CD146-positive tumors., PMID:27065325
Antitumor immunization of mothers delays tumor development in cancer-prone offspring., PMID:26155401
Angiomotin is a novel component of cadherin-11/β-catenin/p120 complex and is critical for cadherin-11-mediated cell migration., PMID:25466890
Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation., PMID:24225952
Soluble melanoma cell adhesion molecule (sMCAM/sCD146) promotes angiogenic effects on endothelial progenitor cells through angiomotin., PMID:23389031
A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors., PMID:22426512
Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo., PMID:17984175
Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties., PMID:17397395
A DNA vaccine targeting angiomotin inhibits angiogenesis and suppresses tumor growth., PMID:16754857
Angiomotin and angiomotin like proteins, their expression and correlation with angiogenesis and clinical outcome in human breast cancer., PMID:16430777
Targeting angiogenesis with antibodies for the treatment of cancer., PMID:16118694
For research use only. Not for human or drug use.
