Catalog No.
PHK70801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PIKFYVE (Ala1864-Cys2098).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Serine-protein kinase PIKFYVE, Phosphatidylinositol 3-phosphate 5-kinase, PIKfyve, 1-phosphatidylinositol 3-phosphate 5-kinase, PIKFYVE, FYVE finger-containing phosphoinositide kinase, Type III PIP kinase, PIPkin-III, KIAA0981, PIP5K3, Phosphatidylinositol 3-phosphate 5-kinase type III
Purification
Purified by antigen affinity column.
Accession
Q9Y2I7
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Phase II trial of multi-tyrosine kinase inhibitor ESK981 in combination with PD-1 inhibitor nivolumab in patients with metastatic castration-resistant prostate cancer., PMID:39503807
Autophagy Blockage Up-Regulates HLA-Class-I Molecule Expression in Lung Cancer and Enhances Anti-PD-L1 Immunotherapy Efficacy., PMID:39409895
Complete Protection from SARS-CoV-2 Lung Infection in Mice Through Combined Intranasal Delivery of PIKfyve Kinase and TMPRSS2 Protease Inhibitors., PMID:37503261
Ribosomal targeting strategy and nuclear labeling to analyze photoreceptor phosphoinositide signatures., PMID:35427794
Loss of PIKfyve drives the spongiform degeneration in prion diseases., PMID:34291577
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV., PMID:32221306
PIKfyve sensitivity of hERG channels., PMID:23735862
Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40., PMID:14530284
Selective insulin-induced activation of class I(A) phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes., PMID:11476939
Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells., PMID:9858586
For research use only. Not for human or drug use.
