Catalog No.
PHK70201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NDRG1 (Asp31-Met315).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Differentiation-related gene 1 protein, CAP43, Reducing agents and tunicamycin-responsive protein, N-myc downstream-regulated gene 1 protein, Rit42, RTP, NDRG1, Protein NDRG1, DRG-1, Nickel-specific induction protein Cap43, DRG1
Purification
Purified by antigen affinity column.
Accession
Q92597
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
NDRG1 enhances the sensitivity to Cetuximab by promoting Stat1 ubiquitylation in colorectal cancer., PMID:39128702
MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis., PMID:36862005
NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance., PMID:36357486
Molecular classification of human papillomavirus-positive cervical cancers based on immune signature enrichment., PMID:36203656
Machine Learning-Based Single Cell and Integrative Analysis Reveals That Baseline mDC Predisposition Correlates With Hepatitis B Vaccine Antibody Response., PMID:34777332
NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer., PMID:34385595
A Small Hypoxia Signature Predicted pCR Response to Bevacizumab in the Neoadjuvant GeparQuinto Breast Cancer Trial., PMID:31932495
Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein NDRG1., PMID:31189653
Cell and context-dependent sorting of neuropathy-associated protein NDRG1 - insights from canine tissues and primary Schwann cell cultures., PMID:31029158
Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation., PMID:30815844
Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome., PMID:30582284
HER2 Activation Factors in Arsenite-Exposed Bladder Epithelial Cells., PMID:30137596
Differential time-dependent transcriptional changes in the osteoblast lineage in cortical bone associated with sclerostin antibody treatment in ovariectomized rats., PMID:29955627
Identification of differential phosphorylation and sub-cellular localization of the metastasis suppressor, NDRG1., PMID:29679718
The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells., PMID:28346422
Reciprocal regulation of mTOR complexes in pancreatic islets from humans with type 2 diabetes., PMID:28004151
Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis., PMID:27793840
Novel serum autoantibodies against talin1 in multiple sclerosis: Possible pathogenetic roles of the antibodies., PMID:26025055
Osteopontin-c mediates the upregulation of androgen responsive genes in LNCaP cells through PI3K/Akt and androgen receptor signaling., PMID:25789054
Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system., PMID:24687281
A comparative study of ERG status assessment on DNA, mRNA, and protein levels using unique samples from a Swedish biopsy cohort., PMID:24517914
Global gene expression analysis reveals a link between NDRG1 and vesicle transport., PMID:24498060
Quantitative analysis of BTF3, HINT1, NDRG1 and ODC1 protein over-expression in human prostate cancer tissue., PMID:24386364
WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury., PMID:22700866
The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms., PMID:21398495
NDRG1 protein overexpression in malignant thyroid neoplasms., PMID:20835551
Mammostrat as a tool to stratify breast cancer patients at risk of recurrence during endocrine therapy., PMID:20615243
Overexpression of Cap43 gene in supraglottic laryngeal squamous cell carcinoma., PMID:19460198
Chemosensitivity and stratification by a five monoclonal antibody immunohistochemistry test in the NSABP B14 and B20 trials., PMID:18927301
Preparation and application of monoclonal antibody against hNDRG2., PMID:18758694
Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy., PMID:18692117
Differential expression patterns of NDRG family proteins in the central nervous system., PMID:17998568
A quantitative analysis of N-myc downstream regulated gene 2 (NDRG 2) in human tissues and cell lysates by reverse-phase protein microarray., PMID:17936257
Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter., PMID:17909017
A retroviral vector for siRNA expression in mammalian cells., PMID:17652791
Novel prognostic immunohistochemical biomarker panel for estrogen receptor-positive breast cancer., PMID:16809728
Translation initiation in Leishmania major: characterisation of multiple eIF4F subunit homologues., PMID:15694484
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3., PMID:15461589
N-myc downstream-regulated gene 1 expression in injured sciatic nerves., PMID:15293230
Cellular distribution of NDRG1 protein in the rat kidney and brain during normal postnatal development., PMID:14566023
cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells., PMID:12730682
Expression of NDRG1, a differentiation-related gene, in human tissues., PMID:12432451
Differential expression of the RTP/Drg1/Ndr1 gene product in proliferating and growth arrested cells., PMID:10395947
A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms., PMID:9251681
For research use only. Not for human or drug use.
