Catalog No.
PHA77601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human LIAS (Met86-Tyr309).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LS, LAS, Lipoic acid synthase, Lipoyl synthase, mitochondrial, Lipoate synthase, Lip-syn, LIAS
Purification
Purified by antigen affinity column.
Accession
O43766
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Clinically Relevant Cutoffs for Anti-Extractable Nuclear Antigen Line Immunoassays., PMID:40460086
A novel anti-C6 based approach for IgG avidity testing in Lyme borreliosis: A proof-of-concept study., PMID:40188988
Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes., PMID:39930254
A comparative study evaluating three line immunoassays available for serodiagnosis of equine Lyme borreliosis: Detection of Borrelia burgdorferi sensu lato-specific antibodies in serum samples of vaccinated and non-vaccinated horses., PMID:39715214
Immunogenicity Assessment of a 14-Valent Human Papillomavirus Vaccine Candidate in Mice., PMID:39591165
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5., PMID:39223355
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype., PMID:39059380
Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies., PMID:39019011
Clinical and economic implications of false-positive heparin-induced thrombocytopenia immunoassays: utility of the 4T score., PMID:38874904
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex., PMID:38849365
Assessing the sensitivity and specificity of myositis-specific and associated autoantibodies: a sub-study from the MyoCite cohort., PMID:38479813
Association of Systemic Markers of Inflammation with Signs and Symptoms of Dry Eye Disease and Sjogren's Syndrome in the Dry Eye Assessment and Management (DREAM©) Study., PMID:38345056
Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens., PMID:38299155
Identification of 6 cuproptosis-related genes for active ulcerative colitis with both diagnostic and therapeutic values., PMID:37904461
The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites., PMID:37713419
Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection., PMID:37437014
Detection of Borrelia burgdorferi Sensu-Lato-Specific Antibodies in Sera of Canine and Equine Origin-A Comparative Study with Two Line Immunoassays., PMID:36423082
Impact of a blood-stage vaccine on Plasmodium vivax malaria., PMID:35664997
Heterotypic interactions drive antibody synergy against a malaria vaccine candidate., PMID:35177602
Author Correction: T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial., PMID:34021278
Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses., PMID:33958800
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials., PMID:33617777
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial., PMID:33335323
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses., PMID:33335322
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial., PMID:33220855
New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis., PMID:32750408
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial., PMID:32702298
Evaluation of 12 different assays for detecting ANCA in Chinese patients with GPA and MPA: a multicenter study in China., PMID:31414304
Evaluation of a Novel Microarray Immunoblot Assay for Detection of IgM- and IgG-Class Antibodies to Borrelia burgdorferi., PMID:30135227
Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL® HIT-Ab(PF4-H)] for the diagnosis of immune heparin-induced thrombocytopenia., PMID:28391124
Refolding of Aggregation-Prone ScFv Antibody Fragments Assisted by Hydrophobically Modified Poly(sodium acrylate) Derivatives., PMID:27548824
Autoantibody profiling in APS., PMID:25228721
Exploitation of rolling circle amplification for the construction of large phage-display antibody libraries., PMID:24681277
Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase., PMID:24341803
New route for fast detection of antibodies against zoonotic pathogens in sera of slaughtered pigs by means of flow-through chemiluminescence immunochips., PMID:23611726
Electroporation-aided DNA immunization generates polyclonal antibodies against the native conformation of human endothelin B receptor., PMID:21688998
Occurrence of antibodies to low-incidence antigens among a cohort of multiply transfused patients with sickle cell disease., PMID:22822516
New HLA class I epitopes defined by murine monoclonal antibodies., PMID:20156507
Novel method for quantitative ANA measurement using near-infrared imaging., PMID:19720064
Cynomolgus macaques immunized with two HIV-1 Tat stabilized proteins raise strong and long-lasting immune responses with a pattern of Th1/Th2 response differing from that in mice., PMID:19607953
Curative properties of antibodies against prion protein: a comparative in vitro study of monovalent fragments and divalent antibodies., PMID:19232746
Epitopes of HLA-A, B, C, DR, DQ, DP and MICA antigens., PMID:20524293
Generating antibodies against the native form of the human prion protein (hPrP) in wild-type animals: a comparison between DNA and protein immunizations., PMID:19027745
Polyclonal anti-idiotypic antibodies which mimic an epitope of the human prion protein., PMID:19012967
[Analysis of antibody reactivity for FDP D-dimer fragments by Western blotting]., PMID:18646629
Intrathecal antitreponemal antibody synthesis determination using the INNO-LIA Syphilis Score., PMID:18204743
Assessment of recent HIV-1 infection by a line immunoassay for HIV-1/2 confirmation., PMID:18052604
Comparison of different test systems for simultaneous autoantibody detection in connective tissue diseases., PMID:16014549
Prevalence of HIV-1 non-B subtypes, syphilis, HTLV, and hepatitis B and C viruses among immigrant sex workers in Madrid, Spain., PMID:15484270
The importance of antibodies against low-incidence RBC antigens in complete and abbreviated cross-matching., PMID:12823754
For research use only. Not for human or drug use.
