Catalog No.
PHE82701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DNA2 (Met1-Arg599).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DNA replication ATP-dependent helicase-like homolog, KIAA0083, hDNA2, DNA2, DNA2L, DNA replication ATP-dependent helicase/nuclease DNA2
Purification
Purified by antigen affinity column.
Accession
P51530
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
DNA Conformation-Regulated Hemin Switch for Lab-on-Chip Chemiluminescent Detection of an Antibody Secreted from Hybridoma Cells., PMID:39503400
One-tube B7-H3 detection based on isothermal exponential amplification and dendritic hybridization chain reaction., PMID:38633035
Electrochemical biosensing for E.coli detection based on triple helix DNA inhibition of CRISPR/Cas12a cleavage activity., PMID:38057050
Proximity hybridization regulated dual-mode ratiometric biosensor for estriol detection in pregnancy serum., PMID:37709442
Washing-free electrogenerated chemiluminescence magnetic microbiosensors based on target assistant proximity hybridization for multiple protein biomarkers., PMID:36965986
Universal point-of-care detection of proteins based on proximity hybridization-mediated isothermal exponential amplification., PMID:35332897
Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination., PMID:34926456
A general scattering proximity immunoassay with the formation of dimer of gold nanoparticle., PMID:34215130
A novel electrochemical immunosensor for hepatitis B surface antigen based on Fe3O4 nanoflowers and heterogeneous chain reaction signal amplification strategy., PMID:33076081
Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions., PMID:32555206
Electrochemical detection of β-lactoglobulin based on a highly selective DNA aptamer and flower-like Au@BiVO4 microspheres., PMID:32475386
Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly., PMID:32358495
An anchored monopodial DNA walker triggered by proximity hybridization for amplified amperometric biosensing of nucleic acid and protein., PMID:32200901
Separation-Free Electrogenerated Chemiluminescence Immunoassay Incorporating Target Assistant Proximity Hybridization and Dynamically Competitive Hybridization of a DNA Signal Probe., PMID:31808341
Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks., PMID:30518856
An ultrasensitive electrochemical immunoassay based on a proximity hybridization-triggered three-layer cascade signal amplification strategy., PMID:30465676
Highly sensitive electrochemical immunosensor for golgi protein 73 based on proximity ligation assay and enzyme-powered recycling amplification., PMID:30327105
Electrochemiluminescent Imaging for Multi-immunoassay Sensitized by Dual DNA Amplification of Polymer Dot Signal., PMID:29847924
Proximity Hybridization-Regulated Immunoassay for Cell Surface Protein and Protein-Overexpressing Cancer Cells via Electrochemiluminescence., PMID:29433314
Target-induced cyclic DNAzyme formation for colorimetric and chemiluminescence imaging assay of protein biomarkers., PMID:28879360
Highly Effective Protein Converting Strategy for Ultrasensitive Electrochemical Assay of Cystatin C., PMID:27104623
Homogeneous electrochemical immunoassay of aflatoxin B1 in foodstuff using proximity-hybridization-induced omega-like DNA junctions and exonuclease III-triggered isothermal cycling signal amplification., PMID:26960904
Target-regulated proximity hybridization with three-way DNA junction for in situ enhanced electronic detection of marine biotoxin based on isothermal cycling signal amplification strategy., PMID:25747510
Immunoreaction-triggered DNA assembly for one-step sensitive ratiometric electrochemical biosensing of protein biomarker., PMID:25460904
A novel signal-on strategy for M.SssI methyltransfease activity analysis and inhibitor screening based on photoelectrochemical immunosensor., PMID:25460890
Strip biosensor for amplified detection of nerve growth factor-beta based on a molecular translator and catalytic DNA circuit., PMID:25068151
Ratiometric electrochemical proximity assay for sensitive one-step protein detection., PMID:24618513
Time-resolved fluorescence based DNA detection using novel europium ternary complex doped silica nanoparticles., PMID:19836584
Design parameters to control synthetic gene expression in Escherichia coli., PMID:19759823
Human Dna2 is a nuclear and mitochondrial DNA maintenance protein., PMID:19487465
Dynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replication., PMID:12024033
Novel DNA-protein complex and a large DNA in SLE cryoprecipitates., PMID:3802574