Catalog No.
PHK69201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAB1B (Met1-Gly176).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RAB1B, Ras-related protein Rab-1B
Purification
Purified by antigen affinity column.
Accession
Q9H0U4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence., PMID:38559361
Rab1a regulates sorting of early endocytic vesicles., PMID:24407591
Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation., PMID:23611601
Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways., PMID:23188820
Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment., PMID:21680502
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1., PMID:21378754
Identification and characterisation of novel Mss4-binding Rab GTPases., PMID:21194374
Rab1b silencing using small interfering RNA for analysis of disease-specific function., PMID:18413237
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association., PMID:17429068
Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells., PMID:14680817
Mutant Rab24 GTPase is targeted to nuclear inclusions., PMID:12323076
Membrane targeting of a Rab GTPase that fails to associate with Rab escort protein (REP) or guanine nucleotide dissociation inhibitor (GDI)., PMID:11389151
Inactive and active mutants of rab1b are not tightly integrated into target membranes., PMID:10493955
Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes., PMID:7592724
Guanine nucleotide dissociation inhibitor is essential for Rab1 function in budding from the endoplasmic reticulum and transport through the Golgi stack., PMID:8089173
Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro., PMID:8376457
Multiple GTP-binding proteins regulate vesicular transport from the ER to Golgi membranes., PMID:1447289
GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex., PMID:1429835
Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments., PMID:1918138
For research use only. Not for human or drug use.
