Catalog No.
PHA16101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DDX3X (Glu161-Ser410).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DEAD box, X isoform, CAP-Rf, DDX3, HLP2, DEAD box protein 3, X-chromosomal, DDX3X, ATP-dependent RNA helicase DDX3X, Helicase-like protein 2, DBX
Purification
Purified by antigen affinity column.
Accession
O00571
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Biological and Clinical Relevance of Genetic Alterations in Peripheral T-cell Lymphomas., PMID:40416001
A genome wide CRISPR screen reveals novel determinants of long-lived plasma cell secretory capacity., PMID:40060628
The Circadian Clock Component RORA Increases Immunosurveillance in Melanoma by Inhibiting PD-L1 Expression., PMID:38718296
The 3' terminal region of Zika virus RNA contains a conserved G-quadruplex and is unfolded by human DDX17., PMID:37774422
Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins., PMID:37705009
Copy Number Alteration and Mutational Profile of High-Grade B-Cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements, Diffuse Large B-Cell Lymphoma with MYC-Rearrangement, and Diffuse Large B-Cell Lymphoma with MYC-Cluster Amplification., PMID:36497332
RNA G-quadruplex structures control ribosomal protein production., PMID:34815422
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway., PMID:34614429
The protein landscape of chronic lymphocytic leukemia., PMID:34189564
Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)., PMID:33405951
Combination of anti-PD-1 antibody with P-GEMOX as a potentially effective immunochemotherapy for advanced natural killer/T cell lymphoma., PMID:33376237
DDX3 Participates in Translational Control of Inflammation Induced by Infections and Injuries., PMID:30373933
Medulloblastoma, WNT-activated/SHH-activated: clinical impact of molecular analysis and histogenetic evaluation., PMID:29582169
The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer., PMID:28435452
Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells., PMID:27300509
Modulation of the type I interferon pathways by culture-adaptive hepatitis C virus core mutants., PMID:22616990
Characterization of the endothelial cell cytoskeleton following HLA class I ligation., PMID:22247778
Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation., PMID:21709606
Human DDX3 functions in translation and interacts with the translation initiation factor eIF3., PMID:18628297
For research use only. Not for human or drug use.
