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Anti-Human CNP Polyclonal Antibody

Catalog #:   PHC41601 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P09543
Overview

Catalog No.

PHC41601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CNP (Glu40-Gly396).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CNPase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, CNP

Purification

Purified by antigen affinity column.

Accession

P09543

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with CNP antibody (PHC41601) at 1μg/ml.

    Lane 1: HepG2 cell lysate
    Lane 2: U251 cell lysate
    Lane 3: Hela cell lysate
    Lane 4: Mouse brain lysate
    Lane 5: Mouse cerebellum lysate
    Lane 6: Rat brain lysate
    Lane 7: Rat cerebellum lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 48 kDa
    Observed MW: 45 kDa
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CNP antibody (PHC41601) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 43 kDa
    Observed MW: 43 kDa
References

MIF regulates T helper 17 cell differentiation by activating the p38 MAPK signaling pathway to drive the pathogenesis of EAP., PMID:40440956

Antigen-specific immune therapy (CNP-106) for treatment of generalised myasthenia gravis: rationale and design of first-in-human randomised controlled trial., PMID:39720510

Cascade Amplifying Electrochemical Bioanalysis for Zearalenone Detection in Agricultural Products: Utilizing a Glucose-Fenton-HQ System on Bimetallic-ZIF@CNP Nanocomposites., PMID:39410226

Fluoroamphiphiles for enhancing immune response of subunit vaccine against SARS-CoV-2., PMID:39383977

Recurrent pancreatic cancer treated with N-803 and PD-L1 t-haNK followed by an EGFR-targeted nanocell drug conjugate., PMID:39373598

Using jitter analysis with concentric needle electrodes to assess disease status and treatment responses in myasthenia gravis., PMID:39224193

Use of interleukin-6 receptor antibodies in the second and third trimester of pregnancy: a retrospective cohort study., PMID:39116898

Efficient Production of Self-Assembled Bioconjugate Nanovaccines against Klebsiella pneumoniae O2 Serotype in Engineered Escherichia coli., PMID:38668222

Promising horizons in achondroplasia along with the development of new drugs., PMID:38569854

Homozygous CNP Mutation and Neurodegeneration in Weimaraners: Myelin Abnormalities and Accumulation of Lipofuscin-like Inclusions., PMID:38397235

A therapeutic antibody targeting annexin-A1 inhibits cancer cell growth in vitro and in vivo., PMID:38200229

Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer., PMID:37882661

Vertical Flow Immunoassay Based on Carbon Black Nanoparticles for the Detection of IgG against SARS-CoV-2 Spike Protein in Human Serum: Proof-of-Concept., PMID:37754091

Shedding New Light: Novel Therapies for Achondroplasia and Growth Disorders., PMID:37704353

Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis., PMID:37652913

Nigella sativa-chitosan nanoparticles: Novel intestinal mucosal immunomodulator controls and protects against Salmonella enterica serovar Enteritidis infection in broilers., PMID:37528439

Enhancing effect of chitosan nanoparticles on the immune efficacy of Bordetella bronchiseptica outer membrane vesicles., PMID:37451023

Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles., PMID:37376091

Increasing reproducibility in preclinical stroke research: the correlation of immunofluorescence intensity measurements and Western blot analyses strongly depends on antibody clonality and tissue pre-treatment in a mouse model of focal cerebral ischemia., PMID:37342767

Exploring Toxin Genes of Myanmar Russell's Viper, Daboia siamensis, through De Novo Venom Gland Transcriptomics., PMID:37235344

In silico design and in vivo evaluation of two multi-epitope vaccines containing build-in adjuvant with chitosan nanoparticles against uropathogenic Escherichia coli., PMID:37012877

Cationic PLGA Nanoparticle Formulations as Biocompatible Immunoadjuvant for Serum Production and Immune Response against Bothrops jararaca Venom., PMID:36548785

Development of carbon nanoparticles-based soluble solid-phase immune sensor for the quantitative diagnosis of inflammation., PMID:36473421

Nanoformulated Recombinant Human Myelin Basic Protein and Rituximab Modulate Neuronal Perturbations in Experimental Autoimmune Encephalomyelitis in Mice., PMID:36105617

Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles., PMID:36095190

Biochemistry and toxicology of proteins and peptides purified from the venom of Vipera berus berus., PMID:35769869

Atezolizumab plus carboplatin and nab-paclitaxel versus carboplatin and nab-paclitaxel as treatments for Chinese, treatment-naïve, stage IV, non-squamous, non-small-cell lung cancer patients: A retrospective analysis., PMID:35568997

Diagnosis and management of covid-19 in pregnancy., PMID:35473709

Lysosomal storage disease associated with a CNP sequence variant in Dalmatian dogs., PMID:35447247

Electrophysiology of Guillain-Barré syndrome in Bangladesh: A prospective study of 312 patients., PMID:35112034

NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance., PMID:34866134

Salmonella chitosan nanoparticle vaccine administration is protective against Salmonella Enteritidis in broiler birds., PMID:34784366

Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York., PMID:34373458

Multifocal motor neuropathy and visual pathway impairment: A case report., PMID:34307969

RNA-dependent assembly of chimeric antigen nanoparticles as an efficient H5N1 pre-pandemic vaccine platform., PMID:34256061

An intrinsically bioactive hydrogel with on-demand drug release behaviors for diabetic wound healing., PMID:34095619

Electroencephalographic findings in Bickerstaff's brainstem encephalitis: A possible reflection of the dysfunction of the ascending reticular activating system., PMID:33490740

Fluorescence Signal Enhancement in Antibody Microarrays Using Lightguiding Nanowires., PMID:33467141

BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293

Impaired conduction of Ia sensory fibers in multifocal motor neuropathy: An electrophysiological demonstration., PMID:32913936

Brucellosis causing subacute motor polyradiculopathy and the pathological correlation of pseudomyopathic electromyography: A case report., PMID:32642603

A Phase II Trial of Safety, Tolerability and Immunogenicity of V114, a 15-Valent Pneumococcal Conjugate Vaccine, Compared With 13-Valent Pneumococcal Conjugate Vaccine in Healthy Infants., PMID:32639460

C-type natriuretic peptide stimulates osteoblastic proliferation and collagen-X expression but suppresses fibroblast growth factor-23 expression in vitro., PMID:32517762

Atezolizumab in Combination With Carboplatin and Nab-Paclitaxel in Advanced Squamous NSCLC (IMpower131): Results From a Randomized Phase III Trial., PMID:32302702

Chitosan and chitosan nanoparticles as adjuvant in local Rift Valley Fever inactivated vaccine., PMID:32089983

Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy., PMID:31907603

Atezolizumab First-Line Combination Therapy: A Review in Metastatic Nonsquamous NSCLC., PMID:31728860

Rapid detection of the main carbapenemases in Brazil directly from spiked blood culture using the RESIST-3 O.K.N. immunoassay., PMID:31270693

Nucleic acid lateral flow assays using a conjugate of a DNA binding protein and carbon nanoparticles., PMID:31187248

Stimulated single-fiber electromyography (sSFEMG) in Lambert-Eaton syndrome., PMID:30215026

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human CNP Polyclonal Antibody [PHC41601]
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