Catalog No.
PHK13001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TRPV6/ECaC2 (Ser87-Asp319).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CaT1, Transient receptor potential cation channel subfamily V member 6, CaT-like, TrpV6, CaT-L, ECAC2, TRPV6, ECaC2, Epithelial calcium channel 2, Calcium transport protein 1
Purification
Purified by antigen affinity column.
Accession
Q9H1D0
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Trpv6 channel targeting using monoclonal antibody induces prostate cancer cell apoptosis and tumor regression., PMID:38879621
TRPV6 Calcium Channel Targeting by Antibodies Raised against Extracellular Epitopes Induces Prostate Cancer Cell Apoptosis., PMID:36980711
A Novel Anti-TRPV6 Antibody and Its Application in Cancer Diagnosis In Vitro., PMID:36613866
Vitamin D receptor is overexpressed in the duodenum of patients with irritable bowel syndrome., PMID:32839988
Antibody-induced internalisation of retroviral envelope glycoproteins is a signal initiation event., PMID:32453763
Parathyroid Hormone-Related Protein (1-40) Enhances Calcium Uptake in Rat Enterocytes Through PTHR1 Receptor and Protein Kinase Cα/β Signaling., PMID:30504697
Transient receptor potential vanilloid 6 (TRPV6) in the mouse brain: Distribution and estrous cycle-related changes in the hypothalamus., PMID:28039038
The role of calbindin-D28k on renal calcium and magnesium handling during treatment with loop and thiazide diuretics., PMID:26582761
Modulation of small intestinal phosphate transporter by dietary supplements of mineral phosphorus and phytase in broilers., PMID:25834252
Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle., PMID:25820697
Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity., PMID:23968883
The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG., PMID:23612980
Expression of Transient Receptor Potential Vanilloid (TRPV) channels in different passages of articular chondrocytes., PMID:22605988
Generation and analysis of the thiazide-sensitive Na+ -Cl- cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndrome., PMID:20848653
Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium., PMID:20405023
Expression and immunolocalization of calcium transport proteins in the canine duodenum, kidney, and pancreas., PMID:20186965
Mechanisms for hypercalciuria in pseudohypoaldosteronism type II-causing WNK4 knock-in mice., PMID:20181799
Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth., PMID:20113508
Tamoxifen inhibits TRPV6 activity via estrogen receptor-independent pathways in TRPV6-expressing MCF-7 breast cancer cells., PMID:19996302
The specific activation of TRPC4 by Gi protein subtype., PMID:18854172
Milk fermentation products of L. helveticus R389 activate calcineurin as a signal to promote gut mucosal immunity., PMID:17825099
Effect of thiazide on renal gene expression of apical calcium channels and calbindins., PMID:15265769
The TRPV6 gene, cDNA and protein., PMID:12765696
Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies., PMID:12480925
For research use only. Not for human or drug use.
