Catalog No.
PHK67401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TBX5 (Gln43-Lys253).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
T-box protein 5, T-box transcription factor TBX5, TBX5
Purification
Purified by antigen affinity column.
Accession
Q99593
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Challenges in Identifying the Cause of Fetal Sinus Bradycardia: Coexistence of Maternal Anti-SSA Antibodies and Holt-Oram Syndrome Due to a Novel TBX5 Variant., PMID:40059089
Insertion of a FLAG-tag sequence at the end of exon 9 of the TBX5 gene in three induced pluripotent stem cell lines (DHMi004-A-4, DHMi004-A-5, DHMi004-A-6) by CRISPR/Cas9 technology., PMID:38100916
Generation of two CRISPR/Cas edited human induced pluripotent stem cell lines (DHMi005-A-3 and DHMi005-A-4) carrying a FLAG-tag after exon 9 of the TBX5 gene., PMID:36610218
The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution., PMID:34084162
Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation., PMID:34062094
The oncoprotein TBX3 is controlling severity in experimental arthritis., PMID:30630509
Complement component C3aR constitutes a novel regulator for chick eye morphogenesis., PMID:28576690
Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts., PMID:28362413
Expression of T-box transcription factors 2, 4 and 5 is decreased in the branching airway mesenchyme of nitrofen-induced hypoplastic lungs., PMID:27833996
Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers., PMID:27036009
Novel exons in the tbx5 gene locus generate protein isoforms with distinct expression domains and function., PMID:25623069
Regulatory modulation of the T-box gene Tbx5 links development, evolution, and adaptation of the sternum., PMID:25468972
Glucosamine-induced OGT activation mediates glucose production through cleaved Notch1 and FoxO1, which coordinately contributed to the regulation of maintenance of self-renewal in mouse embryonic stem cells., PMID:24730386
Pax3 and Tbx5 specify whether PDGFRα+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells., PMID:24677751
Islet-1 may function as an assistant factor for histone acetylation and regulation of cardiac development-related transcription factor Mef2c expression., PMID:24147056
Accelerated direct reprogramming of fibroblasts into cardiomyocyte-like cells with the MyoD transactivation domain., PMID:23794713
In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor., PMID:23316332
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos., PMID:22438573
Directed differentiation of human embryonic stem cells to interrogate the cardiac gene regulatory network., PMID:21694703
HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors., PMID:20454457
Generation of functional murine cardiac myocytes from induced pluripotent stem cells., PMID:18625890
Common marmoset embryonic stem cell can differentiate into cardiomyocytes., PMID:18331825
Induction of initial heart alpha-actin, smooth muscle alpha-actin, in chick pregastrula epiblast: the role of hypoblast and fibroblast growth factor-8., PMID:18312428
STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction., PMID:17823373
Tbx5 is dispensable for forelimb outgrowth., PMID:17138667
Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5., PMID:15537493
Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis., PMID:15136151
Identification and localization of TBX5 transcription factor during human cardiac morphogenesis., PMID:10974675
For research use only. Not for human or drug use.
