Catalog No.
PHB68701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TDP2 (Gly111-Leu362).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Tyr-DNA phosphodiesterase 2, TDP2, hTDP2, 5'-tyrosyl-DNA phosphodiesterase, Tyrosyl-DNA phosphodiesterase 2, EAP2, Tyrosyl-RNA phosphodiesterase, EAPII, TTRAP, VPg unlinkase, 5'-Tyr-DNA phosphodiesterase, TRAF and TNF receptor-associated protein, ETS1-associated protein II, ETS1-associated protein 2
Purification
Purified by antigen affinity column.
Accession
O95551
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants., PMID:32887544
Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1)., PMID:32460231
Host genetic background affects the course of infection and treatment response in patients with chronic hepatitis B., PMID:31505315
Increased genomic instability following treatment with direct acting anti-hepatitis C virus drugs., PMID:30139628
Blood-Based Oligomeric and Other Protein Variant Biomarkers to Facilitate Pre-Symptomatic Diagnosis and Staging of Alzheimer's Disease., PMID:28372328
TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function., PMID:24658003
Generation of assays and antibodies to facilitate the study of human 5'-tyrosyl DNA phosphodiesterase., PMID:23416181
An RNA virus hijacks an incognito function of a DNA repair enzyme., PMID:22908287
Oncogenic role of EAPII in lung cancer development and its activation of the MAPK-ERK pathway., PMID:21478903
EAPII interacts with ETS1 and modulates its transcriptional function., PMID:12743594
For research use only. Not for human or drug use.
