Catalog No.
PHD67101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human BRD2 (Arg74-Gln182).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Really interesting new gene 3 protein, KIAA9001, O27.1.1, BRD2, RING3, Bromodomain-containing protein 2
Purification
Purified by antigen affinity column.
Accession
P25440
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
BRD2 promotes antibody class switch recombination by facilitating DNA repair in collaboration with NIPBL., PMID:38567724
cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis., PMID:36414711
Serum BRD2 autoantibody in hepatocellular carcinoma and its detection using mimotope peptide‑conjugated BSA., PMID:36321789
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2., PMID:35027731
PD-L1 is upregulated via BRD2 in head and neck squamous cell carcinoma models of acquired cetuximab resistance., PMID:34346116
Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy., PMID:34267311
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2., PMID:33501440
Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer., PMID:33086530
BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity., PMID:31266503
Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes., PMID:26324948
BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells., PMID:25989842
BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle., PMID:25697361
The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif., PMID:18270511
E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia., PMID:14563639
Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein., PMID:12145330
Identification and cloning of an 85-kDa protein homologous to RING3 that is upregulated in proliferating endothelial cells., PMID:11502199
Stimulation of p85/RING3 kinase in multiple organs after systemic administration of mitogens into mice., PMID:9528865
Rubella vaccine in the People's Republic of China., PMID:4001739
Studies on the reactogenicity and immunogenicity of the BRD-2 and RA27/3 live attenuated rubella vaccines., PMID:6531968
For research use only. Not for human or drug use.
