Anti-Human ATP6V1B1 Polyclonal Antibody

Catalog No.

PHD10301

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ATP6V1B1 (Asp111-Leu513).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

ATP6V1B1, Endomembrane proton pump 58 kDa subunit, V-ATPase subunit B 1, Vacuolar proton pump subunit B 1, VPP3, V-type proton ATPase subunit B, kidney isoform, VATB, ATP6B1

Purification

Purified by antigen affinity column.

Accession

P15313

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Novel concept of Wilms' tumor development: involvement of pluripotential cells of ureteric bud., PMID:37209922

Evidence for the involvement of branchial Vacuolar-type H+-ATPase in the acidification of the external medium by the West African lungfish, Protopterus annectens, exposed to ammonia-loading conditions., PMID:35987338

Downregulated ATP6V1B1 expression acidifies the intracellular environment of cancer cells leading to resistance to antibody-dependent cellular cytotoxicity., PMID:33000417

Novel IQCE variations confirm its role in postaxial polydactyly and cause ciliary defect phenotype in zebrafish., PMID:31549751

Presence of serum autoantibodies to vacuolar H+ -ATPase in patients with renal tubular acidosis., PMID:30821427

H+-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney., PMID:29993276

Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis., PMID:29310826

Dot1l deficiency leads to increased intercalated cells and upregulation of V-ATPase B1 in mice., PMID:26404731

cAMP stimulates apical V-ATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells., PMID:20053793

Association of soluble adenylyl cyclase with the V-ATPase in renal epithelial cells., PMID:17959750

Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice., PMID:17898041

Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis., PMID:16192400

V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice., PMID:15634743

Molecular cloning and characterization of Atp6v1b1, the murine vacuolar H+ -ATPase B1-subunit., PMID:14585495

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