Catalog No.
PHG51201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MYO7A (Met850-Asn1150).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Unconventional myosin-VIIa, MYO7A, USH1B
Purification
Purified by antigen affinity column.
Accession
Q13402
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Hair cell morphological patterns and polarity organization in the sea lamprey vestibular cristae., PMID:36651665
Efferent innervation of turtle semicircular canal cristae: comparisons with bird and mouse., PMID:25560461
Inhibition of repulsive guidance molecule, RGMa, increases afferent synapse formation with auditory hair cells., PMID:24123853
The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65., PMID:21493626
Moderate light-induced degeneration of rod photoreceptors with delayed transducin translocation in shaker1 mice., PMID:21447681
Analysis of subcellular localization of Myo7a, Pcdh15 and Sans in Ush1c knockout mice., PMID:21156003
Function of MYO7A in the human RPE and the validity of shaker1 mice as a model for Usher syndrome 1B., PMID:19643958
Analysis of the linkage of MYRIP and MYO7A to melanosomes by RAB27A in retinal pigment epithelial cells., PMID:17352418
Photoreceptor expression of the Usher syndrome type 1 protein protocadherin 15 (USH1F) and its interaction with the scaffold protein harmonin (USH1C)., PMID:15928608
Differential distribution of harmonin isoforms and their possible role in Usher-1 protein complexes in mammalian photoreceptor cells., PMID:14578428
Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d., PMID:12717441
Myosin VIIA is specifically associated with calmodulin and microtubule-associated protein-2B (MAP-2B)., PMID:11171103
Rhodopsin transport in the membrane of the connecting cilium of mammalian photoreceptor cells., PMID:10891855
Myosin VIIa as a common component of cilia and microvilli., PMID:9678669
Expression of myosin VIIA during mouse embryogenesis., PMID:9278160
Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells., PMID:9227854
Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B., PMID:7568224