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Anti-Human MYO7A Polyclonal Antibody

Catalog #:   PHG51201 Specific References (17) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q13402
Overview

Catalog No.

PHG51201

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MYO7A (Met850-Asn1150).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Unconventional myosin-VIIa, MYO7A, USH1B

Purification

Purified by antigen affinity column.

Accession

Q13402

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with MYO7A antibody (PHG51201) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 37 kDa
    Observed MW: 37 kDa
References

Hair cell morphological patterns and polarity organization in the sea lamprey vestibular cristae., PMID:36651665

Efferent innervation of turtle semicircular canal cristae: comparisons with bird and mouse., PMID:25560461

Inhibition of repulsive guidance molecule, RGMa, increases afferent synapse formation with auditory hair cells., PMID:24123853

The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65., PMID:21493626

Moderate light-induced degeneration of rod photoreceptors with delayed transducin translocation in shaker1 mice., PMID:21447681

Analysis of subcellular localization of Myo7a, Pcdh15 and Sans in Ush1c knockout mice., PMID:21156003

Function of MYO7A in the human RPE and the validity of shaker1 mice as a model for Usher syndrome 1B., PMID:19643958

Analysis of the linkage of MYRIP and MYO7A to melanosomes by RAB27A in retinal pigment epithelial cells., PMID:17352418

Photoreceptor expression of the Usher syndrome type 1 protein protocadherin 15 (USH1F) and its interaction with the scaffold protein harmonin (USH1C)., PMID:15928608

Differential distribution of harmonin isoforms and their possible role in Usher-1 protein complexes in mammalian photoreceptor cells., PMID:14578428

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d., PMID:12717441

Myosin VIIA is specifically associated with calmodulin and microtubule-associated protein-2B (MAP-2B)., PMID:11171103

Rhodopsin transport in the membrane of the connecting cilium of mammalian photoreceptor cells., PMID:10891855

Myosin VIIa as a common component of cilia and microvilli., PMID:9678669

Expression of myosin VIIA during mouse embryogenesis., PMID:9278160

Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells., PMID:9227854

Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B., PMID:7568224

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human MYO7A Polyclonal Antibody [PHG51201]
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