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Anti-Human MAGEC2 Polyclonal Antibody

Catalog #:   PHK63301 Specific References (24) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9UBF1
Overview

Catalog No.

PHK63301

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MAGEC2 (Asp132-Ser328).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

MAGEC2, MAGEE1, HCA587, Cancer/testis antigen 10, MAGE-C2 antigen, MAGE-E1 antigen, CT10, Melanoma-associated antigen C2, Hepatocellular carcinoma-associated antigen 587

Purification

Purified by antigen affinity column.

Accession

Q9UBF1

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with MAGEC2 antibody (PHK63301) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
References

Application of the iPLUS non-coding sequence in improving biopharmaceuticals production., PMID:38380261

Suitability of tumor-associated antibodies as predictive biomarker for response to immune checkpoint inhibitors in patients with melanoma: a short report., PMID:36750254

Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies., PMID:34430349

TriMix and tumor antigen mRNA electroporated dendritic cell vaccination plus ipilimumab: link between T-cell activation and clinical responses in advanced melanoma., PMID:32114500

Integration of IgA and IgG Autoantigens Improves Performance of Biomarker Panels for Early Diagnosis of Lung Cancer., PMID:31924693

Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer., PMID:30736848

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas., PMID:28648905

Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes., PMID:27165065

Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers., PMID:25576290

T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness., PMID:25423330

MAGEC2, an epithelial-mesenchymal transition inducer, is associated with breast cancer metastasis., PMID:24687377

Induction of HCA587-specific antitumor immunity with HCA587 protein formulated with CpG and ISCOM in mice., PMID:23071764

MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors., PMID:21780320

Heteroclitic serological response in esophageal and prostate cancer patients after NY-ESO-1 protein vaccination., PMID:21413013

High expression of cancer testis antigens MAGE-A, MAGE-C1/CT7, MAGE-C2/CT10, NY-ESO-1, and gage in advanced squamous cell carcinoma of the larynx., PMID:20886663

Expression and prognostic relevance of MAGE-C1/CT7 and MAGE-C2/CT10 in osteolytic lesions of patients with multiple myeloma., PMID:20621094

Cancer-testis (CT) antigen expression in medulloblastoma., PMID:18426187

Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation., PMID:17023585

Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma., PMID:16929165

Generation of monoclonal antibodies to cancer/testis (CT) antigen CT10/MAGE-C2., PMID:16594646

HCA587 antigen expression in normal tissues and cancers: correlation with tumor differentiation in hepatocellular carcinoma., PMID:12920247

Expression, purification and serological analysis of hepatocellular carcinoma associated antigen HCA587 in insect cells., PMID:12679909

Immunomic analysis of human sarcoma., PMID:12601173

CT10: a new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational-difference analysis., PMID:10699956

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human MAGEC2 Polyclonal Antibody [PHK63301]
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