Catalog No.
PHK63301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MAGEC2 (Asp132-Ser328).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
MAGEC2, MAGEE1, HCA587, Cancer/testis antigen 10, MAGE-C2 antigen, MAGE-E1 antigen, CT10, Melanoma-associated antigen C2, Hepatocellular carcinoma-associated antigen 587
Purification
Purified by antigen affinity column.
Accession
Q9UBF1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Application of the iPLUS non-coding sequence in improving biopharmaceuticals production., PMID:38380261
Suitability of tumor-associated antibodies as predictive biomarker for response to immune checkpoint inhibitors in patients with melanoma: a short report., PMID:36750254
Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies., PMID:34430349
TriMix and tumor antigen mRNA electroporated dendritic cell vaccination plus ipilimumab: link between T-cell activation and clinical responses in advanced melanoma., PMID:32114500
Integration of IgA and IgG Autoantigens Improves Performance of Biomarker Panels for Early Diagnosis of Lung Cancer., PMID:31924693
Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer., PMID:30736848
Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas., PMID:28648905
Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes., PMID:27165065
Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers., PMID:25576290
T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness., PMID:25423330
MAGEC2, an epithelial-mesenchymal transition inducer, is associated with breast cancer metastasis., PMID:24687377
Induction of HCA587-specific antitumor immunity with HCA587 protein formulated with CpG and ISCOM in mice., PMID:23071764
MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors., PMID:21780320
Heteroclitic serological response in esophageal and prostate cancer patients after NY-ESO-1 protein vaccination., PMID:21413013
High expression of cancer testis antigens MAGE-A, MAGE-C1/CT7, MAGE-C2/CT10, NY-ESO-1, and gage in advanced squamous cell carcinoma of the larynx., PMID:20886663
Expression and prognostic relevance of MAGE-C1/CT7 and MAGE-C2/CT10 in osteolytic lesions of patients with multiple myeloma., PMID:20621094
Cancer-testis (CT) antigen expression in medulloblastoma., PMID:18426187
Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation., PMID:17023585
Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma., PMID:16929165
Generation of monoclonal antibodies to cancer/testis (CT) antigen CT10/MAGE-C2., PMID:16594646
HCA587 antigen expression in normal tissues and cancers: correlation with tumor differentiation in hepatocellular carcinoma., PMID:12920247
Expression, purification and serological analysis of hepatocellular carcinoma associated antigen HCA587 in insect cells., PMID:12679909
Immunomic analysis of human sarcoma., PMID:12601173
CT10: a new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational-difference analysis., PMID:10699956