Catalog No.
PHH07401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PCBP1 (Asn11-Ser173).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PCBP1, Poly(rC)-binding protein 1, Nucleic acid-binding protein SUB2.3, Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, hnRNP E1
Purification
Purified by antigen affinity column.
Accession
Q15365
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Conserved role for PCBP1 in altered RNA splicing in the hippocampus after chronic alcohol exposure., PMID:37537282
Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions., PMID:36592411
Longitudinal change of genetic variations in cetuximab-treated metastatic colorectal cancer., PMID:34315006
PCBP2 Is Downregulated in Degenerating Neurons and Rarely Observed in TDP-43-Positive Inclusions in Sporadic Amyotrophic Lateral Sclerosis., PMID:33313661
lncRNA PCBP1-AS1 Aggravates the Progression of Hepatocellular Carcinoma via Regulating PCBP1/PRL-3/AKT Pathway., PMID:32753957
Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease., PMID:31599037
Multiphosphorylation and cellular localization of poly(rC) binding protein 1 during mitosis in hela cell., PMID:31076991
Identification of gamma-synuclein as a new PCBP1-interacting protein., PMID:26344801
Differential expression of polycytosine-binding protein isoforms in adrenal gland, locus coeruleus and midbrain., PMID:25463520
Specific enrichment of the RNA-binding proteins PCBP1 and PCBP2 in chief cells of the murine gastric mucosa., PMID:24480778
RACK1 identified as the PCBP1-interacting protein with a novel functional role on the regulation of human MOR gene expression., PMID:23173782
The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation., PMID:18656221
Large-scale identification of novel mitosis-specific phosphoproteins., PMID:18373986
Poly C binding protein, a single-stranded DNA binding protein, regulates mouse mu-opioid receptor gene expression., PMID:15836633
A posttranscriptional regulator of Kaposi's sarcoma-associated herpesvirus interacts with RNA-binding protein PCBP1 and controls gene expression through the IRES., PMID:15246275
Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo., PMID:12970749
Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA., PMID:9257647
For research use only. Not for human or drug use.
