Anti-Human EWSR1 Polyclonal Antibody

Catalog No.

PHF89701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human EWSR1 (Asp353-Arg446).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

RNA-binding protein EWS, EWS oncogene, EWS, EWSR1, Ewing sarcoma breakpoint region 1 protein

Purification

Purified by antigen affinity column.

Accession

Q01844

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Pluripotent stem cell marker deficiency in salivary mucoepidermoid carcinoma with relevance to molecular profiling: An experimental study., PMID:40478494

SS18-SSX and SSX c-terminus antibodies for identification of specific fusion oncoprotein in mesenchymal neoplasms., PMID:40128131

SSX and SS18-SSX Antibodies as Additional Tools for Diagnosing Undifferentiated Neoplasms With the EWSR1::SSX3 Fusion., PMID:40119747

Mapping Knowledge Structure and Themes Trends of Ewing Sarcoma: A Text-Mining Study., PMID:39971856

High expression level of ERBB2 and efficacy of trastuzumab deruxtecan in desmoplastic small round cell tumour: a monocentric case series report., PMID:39921935

VGLL fusions define a new class of intraparenchymal central nervous system schwannoma., PMID:39713960

HER2 Antibody-Drug Conjugates Are Active against Desmoplastic Small Round Cell Tumor., PMID:39120576

Myoepithelial tumors of soft tissue and bone in children and young adults: A clinicopathologic study of 40 cases occurring in patients ≤ 21 Years of age., PMID:38782103

Gene of the month: DDIT3., PMID:38053287

Utility of Immunohistochemistry With Antibodies to SS18-SSX Chimeric Proteins and C-Terminus of SSX Protein for Synovial Sarcoma Differential Diagnosis., PMID:37899499

Impact of Amplified Oncogenes on Salivary Gland Carcinomas., PMID:37671310

TRAF3-EWSR1 signaling axis acts as a checkpoint on germinal center responses., PMID:37097293

Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma., PMID:36959380

Extraskeletal myxoid chondrosarcoma: A study of 17 cases focusing on the diagnostic utility of INSM1 expression and presenting rare morphological variants associated with non-EWSR1::NR4A3 fusions., PMID:36563884

Validation of PRKCB Immunohistochemistry as a Biomarker for the Diagnosis of Ewing Sarcoma., PMID:36062956

Gammaherpesvirus-mediated repression reveals EWSR1 to be a negative regulator of B cell responses., PMID:35921433

Desmoplastic Small Round Cell Tumor of the Uterus: A Report of Molecularly Confirmed Case with EWSR1-WT1 Fusion., PMID:35626339

Selective Immunoreactivity for WT1 Carboxy-Terminus Distinguishes Desmoplastic Small Round Cell Tumor From its Histologic Mimics., PMID:35488420

Gene fusions in gastrointestinal tract cancers., PMID:35239225

Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling., PMID:34841430

Identification of novel SSX1 fusions in synovial sarcoma., PMID:34504309

The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution., PMID:34084162

Desmoplastic Small Round Cell Tumor with "Pure" Spindle Cell Morphology and Novel EWS-WT1 Fusion Transcript: Expanding the Morphological and Molecular Spectrum of This Rare Entity., PMID:33803887

Current Status of Management and Outcome for Patients with Ewing Sarcoma., PMID:33801953

Nuclear expression of DDIT3 distinguishes high-grade myxoid liposarcoma from other round cell sarcomas., PMID:33731886

Confirmation of NKX3-1 Expression in EWSR1-NFATC2 Sarcoma and Mesenchymal Chondrosarcoma Using Monoclonal Antibody Immunohistochemistry, RT-PCR, and RNA In Situ Hybridization., PMID:33443863

Extraskeletal Ewing's Sarcoma with CD7 Positivity and T-cell Receptor/Immunoglobulin Rearrangement Masquerading as T-lymphoblastic Lymphoma., PMID:33213248

DDIT3 Immunohistochemistry Is a Useful Tool for the Diagnosis of Myxoid Liposarcoma., PMID:32815829

Angiomatoid Fibrous Histiocytoma With ALK Expression in an Unusual Location and Age Group., PMID:32310859

Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions., PMID:31494268

Desmoplastic small round cell tumor of the parotid gland-report of a rare case and a review of the literature., PMID:31103034

Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma., PMID:30741933

EWSR1 Rearrangement and CD99 Expression as Diagnostic Biomarkers for Ewing/PNET Sarcomas in a Moroccan Population., PMID:30319719

An Uncommon Presentation of a Primary Bone Tumor: Anti-AMPA (Anti-α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid) Receptor Limbic/Paraneoplastic Encephalitis as a Presenting Feature of Ewing Sarcoma., PMID:30247289

High-grade myoepithelial carcinoma can show histologically undifferentiated/anaplastic features., PMID:30236544

EWSR1-SMAD3-rearranged Fibroblastic Tumor: An Emerging Entity in an Increasingly More Complex Group of Fibroblastic/Myofibroblastic Neoplasms., PMID:29957732

Therapeutic response of metastatic angiomatoid fibrous histiocytoma carrying EWSR1-CREB1 fusion to the interleukin-6 receptor antibody tocilizumab., PMID:29932283

PAX7 immunohistochemical evaluation of Ewing sarcoma and other small round cell tumours., PMID:29920735

[Ewing sarcomas and Ewing-like sarcomas : New aspects]., PMID:29480450

Detection of circulating tumor cells in liquid biopsy from Ewing sarcoma patients., PMID:29386915

Hyalinizing Clear Cell Carcinoma of the Lung: Case Report and Review of the Literature., PMID:28927164

Potential approaches to the treatment of Ewing's sarcoma., PMID:27740934

BCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic Abnormalities., PMID:27428733

Ewing sarcoma: The clinical relevance of the insulin-like growth factor 1 and the poly-ADP-ribose-polymerase pathway., PMID:26765686

DOG1 Expression in Low-Grade Fibromyxoid Sarcoma: A Study of 11 Cases, With Molecular Characterization., PMID:26135531

PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced Pulmonary Inflammation., PMID:26026059

Beware of immunohistochemistry--report of a cytokeratin-, desmin- and INI-1-negative pelvic desmoplastic small round cell tumor in a 51 year old woman., PMID:25755805

Small cell osteosarcoma: clinicopathologic, immunohistochemical, and molecular analysis of 36 cases., PMID:25723116

Immunoreactivity using anti-ERG monoclonal antibodies in sarcomas is influenced by clone selection., PMID:24906228

Diagnostic pitfalls of differentiating desmoplastic small round cell tumor (DSRCT) from Wilms tumor (WT): overlapping morphologic and immunohistochemical features., PMID:24832162

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