Anti-Human EIF4B Polyclonal Antibody

Catalog No.

PHD59601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human EIF4B (Thr97-Gln173).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

EIF4B, Eukaryotic translation initiation factor 4B, eIF-4B

Purification

Purified by antigen affinity column.

Accession

P23588

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway., PMID:39694222

Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling., PMID:39393543

Identification of two potential immune-related biomarkers of Graves' disease based on integrated bioinformatics analyses., PMID:35962894

The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism., PMID:24375594

Anthrax lethal toxin inhibits translation of hypoxia-inducible factor 1α and causes decreased tolerance to hypoxic stress., PMID:24366872

Evidence for variation in the optimal translation initiation complex: plant eIF4B, eIF4F, and eIF(iso)4F differentially promote translation of mRNAs., PMID:19493973

Identification and characterization of the expression of the translation initiation factor 4A (eIF4A) from Drosophila melanogaster., PMID:14760701

Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function., PMID:12406227

Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes., PMID:10859165

Eukaryotic initiation factor 4B from wheat and Arabidopsis thaliana is a member of a multigene family., PMID:10600500

Mapping the cleavage site in protein synthesis initiation factor eIF-4 gamma of the 2A proteases from human Coxsackievirus and rhinovirus., PMID:8396129

Epidermal growth factor stimulates phosphorylation of eukaryotic initiation factor 4B, independently of protein kinase C., PMID:8388736

Identification of the 80-kDa protein that crosslinks to the cap structure of eukaryotic mRNAs as initiation factor eIF-4B., PMID:3395129

Identification of two messenger RNA cap binding proteins in wheat germ. Evidence that the 28-kDa subunit of eIF-4B and the 26-kDa subunit of eIF-4F are antigenically distinct polypeptides., PMID:2440886

Translational initiation factors from sea urchin eggs and embryos: functional properties are highly conserved., PMID:3767369

Identification and quantitation of levels of protein synthesis initiation factors in crude HeLa cell lysates by two-dimensional polyacrylamide gel electrophoresis., PMID:6853516

Immunochemical characterization of mammalian protein synthesis initiation factors., PMID:6751385

Association of cap-binding protein with eucaryotic initiation factor 3 in initiation factor preparations from uninfected and poliovirus-infected HeLa cells., PMID:6283140

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