Catalog No.
PHG32601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HYAL2 (Asn74-Gly432).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LUCA2, HYAL2, Hyal-2, LuCa-2, Hyaluronoglucosaminidase-2, Hyaluronidase-2, Lung carcinoma protein 2
Purification
Purified by antigen affinity column.
Accession
Q12891
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Complement protein C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma., PMID:37334363
Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation., PMID:33733989
Therapeutic Zfra4-10 or WWOX7-21 Peptide Induces Complex Formation of WWOX with Selective Protein Targets in Organs that Leads to Cancer Suppression and Spleen Cytotoxic Memory Z Cell Activation In Vivo., PMID:32764489
WWOX Possesses N-Terminal Cell Surface-Exposed Epitopes WWOX7-21 and WWOX7-11 for Signaling Cancer Growth Suppression and Prevention In Vivo., PMID:31752354
High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity., PMID:31526718
Strategies by which WWOX-deficient metastatic cancer cells utilize to survive via dodging, compromising, and causing damage to WWOX-positive normal microenvironment., PMID:31123603
Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer., PMID:28107820
Hyaluronan deposition and co-localization with inflammatory cells and collagen in a murine model of fungal allergic asthma., PMID:24519432
Critical role of hyaluronidase-2 during preimplantation embryo development., PMID:23625939
Expression of endogenous beta retroviruses and Hyal-2 mRNA in immune organs of fetuses and lambs., PMID:22491999
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines., PMID:22139571
HYAL1 overexpression is correlated with the malignant behavior of human breast cancer., PMID:20473947
Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines., PMID:19443707
Mammalian hyaluronidase induces ovarian granulosa cell apoptosis and is involved in follicular atresia., PMID:18653706
Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells., PMID:18390475
Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB., PMID:17324121
Ability of hyaluronidase 2 to degrade extracellular hyaluronan is not required for its function as a receptor for jaagsiekte sheep retrovirus., PMID:17229709
Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells., PMID:16900089
Expression and cellular localization of human hyaluronidase-2 in articular chondrocytes and cultured cell lines., PMID:16600643
Sheep retrovirus structural protein induces lung tumours., PMID:15829964
Improved enzootic nasal tumor virus pseudotype packaging cell lines reveal virus entry requirements in addition to the primary receptor Hyal2., PMID:15596804
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion., PMID:15090545
Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3., PMID:11929860
For research use only. Not for human or drug use.
